IP Library Granted Patent US 11,376,330
Granted Patent B2
US 11,376,330 · App. 17/074,877 · Granted Jul 5, 2022

Compositions and methods for increasing efficiency of cardiac metabolism

Inventor: Andrew D. Levin (Newton, MA)
Assignee: IMBRIA PHARMACEUTICALS, INC.
A61K47/551A61K31/495A61K47/55A61K47/60C07D401/12A61P3/00
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Quick Facts
Patent No.
US 11,376,330
App. No.
17/074,877
Granted
Jul 5, 2022
Kind
B2
Abstract

Compositions and methods for increasing efficiency of cardiac metabolism are provided.

Claims (6)

1. A HCl salt of a compound represented by formula (X):

2. The HCl salt of claim 1 , wherein the salt is a monohydrate.

3. A pharmaceutical composition comprising the HCl salt of claim 1 .

4. The pharmaceutical composition of claim 3 , wherein the composition comprises the compound in a therapeutically effective amount to increase cardiac efficiency in a subject.

5. The pharmaceutical composition of claim 3 , wherein the composition is formulated for oral administration.

6. The pharmaceutical composition of claim 5 , wherein the composition comprises a format selected from the group consisting of a tablet, troche, lozenge, aqueous suspension, oily suspension, emulsion, syrup, hard capsule, and soft capsule.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2021
From: LEVIN, ANDREW
To: RA CAPITAL MANAGEMENT, LLC
Reel/Frame 054857/0832 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2021
From: RA CAPITAL MANAGEMENT, LLC
To: CARNOT, LLC
Reel/Frame 054857/0861 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2021
From: CARNOT, LLC
To: IMBRIA PHARMACEUTICALS, INC.
Reel/Frame 054857/0972 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2021
From: CARNOT, LLC
To: IMBRIA PHARMACEUTICALS, INC.
Reel/Frame 054858/0009 →
Continuity (8)
Continuation 16722754 · Dec 20, 2019
Continuation 16011196 · Jun 18, 2018
Provisional Application 62647926 · Mar 26, 2018
Provisional Application 62637434 · Mar 2, 2018
Provisional Application 62710316 · Feb 16, 2018
Provisional Application 62524237 · Jun 23, 2017
Provisional Application 62522214 · Jun 20, 2017
Related Publication 20210030881A1 · Feb 4, 2021
Cited By (6)
US 12,233,058 US 12,285,428 US 12,318,453 US 12,502,389 US 12,569,480 US 12,649,720