IP Library › Granted Patent US 11,377,480
Granted Patent B2
US 11,377,480 · App. 16/339,710 · Granted Jul 5, 2022

Inducible caspases and methods for use

Inventors: Eric M. Ostertag (San Diego, CA); Devon Shedlock (San Diego, CA)
Assignee: Poseida Therapeutics, Inc.
C07K14/705A61K35/17A61P3/00A61P17/02A61P29/00A61P31/00A61P35/00A61P37/00C07K14/47C07K14/4747C12N5/0636C12N9/50C12N15/52C12Y304/22036
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Quick Facts
Patent No.
US 11,377,480
App. No.
16/339,710
Granted
Jul 5, 2022
Kind
B2
Abstract

The disclosure provides inducible caspase polypeptides, compositions comprising inducible caspase polypeptides and sequences encoding the same, cells modified to express the polypeptides and compositions of the disclosure, as well as methods of making and methods of using same for adoptive cell therapy.

Claims (1)

1. An inducible caspase polypeptide comprising the amino acid sequence of SEQ ID NO: 9.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2019
From: OSTERTAG, ERIC M.; SHEDLOCK, DEVON
To: POSEIDA THERAPEUTICS, INC.
Reel/Frame 048903/0214 →
Continuity (2)
Provisional Application 62405184 · Oct 6, 2016
Related Publication 20190225667A1 · Jul 25, 2019
Cited By (1)
US 12,358,966