IP Library › Granted Patent US 11,382,935
Granted Patent B2
US 11,382,935 · App. 17/554,052 · Granted Jul 12, 2022

Composition for improving cognitive ability and preventing or treating dementia and attention deficit hyperactivity disorder, comprising

Inventor: Seon Ah Ha (Seoul, KR)
Assignees: Sang Hee Kim; Hyun Kee Kim
A61K35/64A61K31/704A61P25/00
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Quick Facts
Patent No.
US 11,382,935
App. No.
17/554,052
Granted
Jul 12, 2022
Kind
B2
Abstract

The present invention relates to a composition for improving cognitive ability, and preventing or treating dementia and a hyperactivity disorder, which includes a Galla rhois extract and fraxin as active ingredients. It was identified that the composition including the Galla rhois extract and fraxin significantly improves cognitive memory in an Alzheimer's disease model induced by Aβ (1-42) administration and an APPswe/PS1dE9 double-expressing Alzheimer's disease model, and inhibits the generation of amyloid plaques, suggesting the usefulness of the combination of the Galla rhois extract and fraxin, as a therapeutic material, against Alzheimer's disease, and showing that the combination of the Galla rhois extract and fraxin is able to be used as a therapeutic agent for ADHD.

Claims (6)

1. A method of preventing or treating dementia, comprising:

administering a composition comprising a Galla rhois extract and fraxin to a subject with dementia or at risk of dementia,

wherein the concentration of the fraxin in the composition is 0.5 mM.

2. A method of improving cognitive ability, comprising:

administering a composition comprising a Galla rhois extract and fraxin to a subject in need of improvement of cognitive ability,

wherein the concentration of the fraxin in the composition is 0.5 mM.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 17, 2021
From: HA, SEON AH
To: KIM, SANG HEE; KIM, HYUN KEE
Reel/Frame 058414/0878 →
Continuity (2)
Continuation 17299227
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