IP Library › Granted Patent US 11,389,423
Granted Patent B2
US 11,389,423 · App. 16/967,334 · Granted Jul 19, 2022

Pharmaceutical composition, excipient for the composition and use of the composition

Inventors: Luiz Donaduzzi (Toledo, BR); Carmen Maria Donaduzzi (Toledo, BR); Liberato Brum Junior (Toledo, BR); Patricia Moura Da Rosa Zimmerman (Toledo, BR); Emanuelle Webler (Toledo, BR); Leticia Mello Rechia (Toledo, BR); José Alexandre Crippa (Ribeirão Preto, BR); Jaime Eduardo Cecilio Hallak (Ribeirão Preto, BR); Antonio Waldo Zuardi (Ribeirão Preto, BR); Francisco Silveira Guimarães (Ribeirão Preto, BR); Alline Cristina De Campos (Ribeirão Preto, BR); Vitor Tumas (Ribeirão Preto, BR); Elaine Aparecida Del Bel Belluz Guimarães (Ribeirão Preto, BR)
Assignees: Prati, Donaduzzi & Cia Ltda; Universidade De São Paulo
A61K31/352A61K31/05A61K47/44A61P25/08A61P25/16A61P25/28A61K9/0053
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Quick Facts
Patent No.
US 11,389,423
App. No.
16/967,334
Granted
Jul 19, 2022
Kind
B2
Abstract

A pharmaceutical composition containing synthetic Cannabidiol and its use in obtaining a medication for the treatment of neurological disorders, as well as the main excipients used in the production process, in addition to its small, medium, and large-scale preparation process. The use of the composition for the treatment of neurological disorders in human or animal populations, in particular in the treatment of Parkinson's disease, in the range of 300 to 850 mg/day or at daily doses of 100 to 1750 mg for neuroprotective action.

Claims (4)

1. A method for neuroprotective action comprising the administration to a human or an animal of a pharmaceutical composition comprising Cannabidiol of synthetic origin, wherein said composition comprises up to 0.06% Cannabinol, up to 0.06% Delta-8-tetrahydrocannabinol, up to 0.06% Delta-9-tetrahydrocannabinol, up to 0.06% Cannabidiolic acid methyl ester, up to 0.06% Menthadienol, and up to 0.06% Methyl olivetolate.

2. The method of treatment according to claim 1 , wherein the administration is at the dose of 100 to 1750 mg/day.

3. The method according to claim 2 , wherein the dose is a single dose or doses divided throughout the day.

4. The method according to claim 1 , wherein the neuroprotective action is for neurological disorders selected from the group consisting of refractory epilepsy, epilepsy, schizophrenia, sleep disorders, post-traumatic disorder, Alzheimer's disease, anxiety, depression, bipolar disorder, neuropathic pain, chronic pain relief, autism, chronic pain relief, and Parkinson's disease.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 4, 2020
From: DONADUZZI, LUIZ; DONADUZZI, CARMEN MARIA; JUNIOR, LIBERATO BRUM; ZIMMERMAN, PATRÍCIA MOURA DA ROSA; WEBLER, EMANUELLE; RECHIA, LETÍCIA MELLO; CRIPPA, JOSÉ ALEXANDRE; HALLAK, JAIME EDUARDO CECILIO; ZUARDI, ANTONIO WALDO; GUIMARÃES, FRANCISCO SILVEIRA; CAMPOS, ALLINE CRISTINA DE; TUMAS, VITOR; GUIMARÃES, ELAINE APARECIDA DEL BEL BELLUZ
To: PRATI, DONADUZZI & CIA LTDA; UNIVERSIDADE DE SÃO PAULO
Reel/Frame 053398/0216 →
Priority Claims (1)
BR 102018002843-0 · Feb 9, 2018 · national
Continuity (1)
Related Publication 20200368197A1 · Nov 26, 2020