IP Library Granted Patent US 11,399,559
Granted Patent B2
US 11,399,559 · App. 15/748,346 · Granted Aug 2, 2022

Nutritional products having improved lipophilic solubility and bioavailability in an easily mixable form

Inventors: Gary Gordon (Plain City, OH); Mustafa Vurma (Dublin, OH)
Assignee: ABBOTT LABORATORIES
A23L33/12A23L29/10A23L33/125A23L33/15A23L33/155A23L33/16A23L33/19A23P10/40A23V2002/00
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,399,559
App. No.
15/748,346
Granted
Aug 2, 2022
Kind
B2
Abstract

Methods of preparing a nutritional product which contain a lipophilic nutrient are disclosed. The nutritional product is made using a fortifying powder containing the lipophilic nutrient, a monoglyceride and diglyceride (“MDG”) oil, a phospholipid, and a carrier. The fortifying powder enhances the digestive absorption of the lipophilic nutrient when the nutritional product is consumed. The fortifying powder simplifies the process of manufacturing the nutritional product, as the fortifying powder can be added at a suitable stage of the process with other powdered ingredients. The fortifying powder may be manufactured in bulk and stored for later use, thereby improving manufacturing efficiencies. The fortifying powder and methods of preparing the fortifying powder are also presented.

Claims (19)

1. A method of preparing a fortifying powder containing a lipophilic nutrient, the method comprising:

a. mixing a lipophilic nutrient, a monoglyceride and diglyceride (MDG) oil, and a phospholipid in the presence of heat to form a first mixture;

b. mixing an aqueous solution comprising a carrier with the first mixture to form a second mixture; and

c. drying the second mixture to form the fortifying powder

wherein:

the MDG oil is present at a concentration of 6 wt % to about 50 wt % of the fortifying powder; and

the phospholipid is present at a concentration of about 1 wt % to about 12 wt % of the fortifying powder.

2. The method of claim 1 wherein the lipophilic nutrient is selected from the group consisting of lutein, zeaxanthin, astaxanthin, beta-carotene, lycopene, Vitamin A, Vitamin D, Vitamin E, Vitamin K, Coenzyme Q10, linoleic acid, alpha linolenic acid, arachidonic acid, docosahexaenoic acid, eicosapentaenoic acid, and combinations thereof.

3. The method of claim 1 wherein the phospholipid is selected from the group consisting of lecithin, choline, phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidic acid, phosphatidyl serine, lysophosphatides, and combinations thereof.

4. The method of claim 1 wherein the lipophilic nutrient and MDG oil are mixed before adding the phospholipid.

5. The method of claim 1 wherein the phospholipid and MDG oil are mixed before adding the lipophilic nutrient.

6. The method of claim 1 wherein the step of drying the second mixture includes freeze drying, spray drying, tray dryers, tunnel dryers, roller dryers, drum dryers, fluidized bed dryers, pneumatic dryers, rotary dryers, trough dryers, bin dryers, belt dryers, vacuum dryers, or combinations thereof.

7. The method of claim 1 , further comprising mixing the fortifying powder with a base nutritional composition to form a nutritional product, wherein the base nutritional composition comprises protein at a concentration of about 1 wt % to about 85 wt % and fat at a concentration of about 0.6 wt % to about 50 wt %.

8. The method of claim 7 wherein the base nutritional composition further comprises carbohydrate at a concentration of about 7 wt % to about 60 wt %.

9. The method of claim 7 wherein the fortifying powder is present at a concentration of about 0.1 wt % to about 16 wt % of the nutritional product.

10. The method of claim 1 , wherein the first mixture is heated to a temperature of at least 85° F. during the mixing step.

11. The method of claim 1 , wherein the first mixture is heated to a temperature of at least 120° F. during the mixing step.

12. The method of claim 1 , wherein the aqueous solution comprises water and the carrier, and wherein the carrier comprises one or more proteins.

13. The method of claim 12 wherein the carrier further comprises one or more ingredients is selected from the group consisting of simple sugars, complex sugars, starches, cellulosics, sugar alcohols, proteins, and combinations thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 22, 2018
From: GORDON, GARY; VURMA, MUSTAFA
To: ABBOTT LABORATORIES
Reel/Frame 045870/0166 →
Continuity (2)
Provisional Application 62198512 · Jul 29, 2015
Related Publication 20180213834A1 · Aug 2, 2018