IP Library › Granted Patent US 11,400,053
Granted Patent B2
US 11,400,053 · App. 16/963,543 · Granted Aug 2, 2022

Patch containing nonylic acid vanillylamide

Inventors: Yusuke Tanaka (Tosu, JP); Masahiro Sato (Tosu, JP); Takaaki Yoshinaga (Tosu, JP)
Assignee: HISAMITSU PHARMACEUTICAL CO., INC.
A61K9/7053A61K31/05A61K31/125A61K31/618A61K36/534A61K47/02A61K47/18
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Quick Facts
Patent No.
US 11,400,053
App. No.
16/963,543
Granted
Aug 2, 2022
Kind
B2
Abstract

The present invention provides a patch comprising a backing layer and an adhesive agent layer, wherein the adhesive agent layer is non-aqueous, the adhesive agent layer contains nonylic acid vanillylamide and aluminum hydroxide, a content of nonylic acid vanillylamide in the adhesive agent layer is 0.01 to 0.025% by mass based on a total mass of the adhesive agent layer, a content of aluminum hydroxide in the adhesive agent layer is 0.55 to 1.5% by mass based on the total mass of the adhesive agent layer, and a mass ratio of the content of nonylic acid vanillylamide to the content of aluminum hydroxide ((content of nonylic acid vanillylamide):(content of aluminum hydroxide)) in the adhesive agent layer is 1:27 to 1:150.

Claims (9)

1. A patch comprising a backing layer and an adhesive agent layer, wherein

the adhesive agent layer is non-aqueous,

the adhesive agent layer contains nonylic acid vanillylamide, aluminum hydroxide and a tackifier wherein the tackifier is at least one selected from the group consisting of a rosin-based resin and a terpene-based resin,

a content of nonylic acid vanillylamide in the adhesive agent layer is 0.012 to 0.025% by mass based on a total mass of the adhesive agent layer,

a content of aluminum hydroxide in the adhesive agent layer is 0.55 to 1.5% by mass based on the total mass of the adhesive agent layer, and

a mass ratio of the content of nonylic acid vanillylamide to the content of aluminum hydroxide ((content of nonylic acid vanillylamide):(content of aluminum hydroxide)) in the adhesive agent layer is 1:27 to 1:150.

2. The patch according to claim 1 , wherein the adhesive agent layer contains at least one anti-inflammatory analgesic agent selected from the group consisting of methyl salicylate, glycol salicylate, l-menthol, dl-camphor, peppermint oil, and thymol.

3. The patch according to claim 2 , wherein a content of the anti-inflammatory analgesic agent in the adhesive agent layer is 1 to 10% by mass based on the total mass of the adhesive agent layer.

4. The patch according to claim 1 , wherein the adhesive agent layer contains at least one rubber-based adhesive base selected from the group consisting of styrene-isoprene-styrene block copolymers, polyisobutylene, styrene-butadiene-styrene block copolymers, natural rubber, polybutene, styrene-butadiene rubber, and isoprene.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2020
From: TANAKA, YUSUKE; SATO, MASAHIRO; YOSHINAGA, TAKAAKI
To: HISAMITSU PHARMACEUTICAL CO., INC.
Reel/Frame 053266/0697 →
Priority Claims (1)
JP JP2018-009834 · Jan 24, 2018 · national
Continuity (1)
Related Publication 20200352873A1 · Nov 12, 2020