Early administration of low-dose colchicine after myocardial infarction

1. A method of treating a patient after having a myocardial infarction (MI), the method comprising initiating the administration of colchicine at a daily low dose to the patient within about 3 days of the MI, wherein the colchicine is administered without pre-loading the patient with a higher dose of colchicine before the administration at the daily low dose, wherein percutaneous coronary intervention was performed for treating the patient's MI.

2. The method according to claim 1 , wherein the patient was prescribed a medication.

3. The method according to claim 2 , wherein the medication is an antiplatelet agent.

4. The method according to claim 2 , wherein the medication is aspirin.

5. The method according to claim 2 , wherein the medication is a statin.

6. The method according to claim 1 , wherein the patient is at a lower risk of a cardiovascular event, relative to a patient not being administered colchicine.

7. The method according to claim 6 , wherein the cardiovascular event is an ischemic cardiovascular event.

8. A method of treating a patient alter having a myocardial infarction (MI), the method comprising initiating the administration of colchicine at a daily low dose to the patient within about 3 days of the MI, wherein the colchicine is administered without pre-loading the patient with a higher dose of colchicine before the administration at the daily low dose, wherein the patient is at a lower risk of a cardiovascular event, relative to a patient not being administered colchicine, and wherein the cardiovascular event is resuscitated cardiac arrest, stroke, or urgent hospitalization for angina requiring coronary revascularization.

9. The method according to claim 6 , wherein the cardiovascular event is myocardial infarction.

10. The method according to claim 8 , wherein the cardiovascular event is stroke.

11. The method according to claim 8 , wherein the cardiovascular event is urgent hospitalization for angina requiring coronary revascularization.

12. The method according to claim 1 , wherein the patient has atherosclerotic coronary artery disease.

13. The method according to claim 1 , wherein the administration of colchicine is initiated upon assessment in (a) an emergency department (ED), (b) the hospital, or (c) a medical office setting.

14. The method according to claim 1 , wherein the colchicine is in the form of a tablet.

15. The method of claim 14 , wherein the tablet is coated.

16. The method of claim 15 , wherein the tablet is film-coated.

17. The method according to claim 1 , wherein the colchicine is administered at 0.3 to 0.7 mg.

18. The method according to claim 17 , wherein the colchicine is administered at 0.4 to 0.6 mg.

19. The method according to claim 18 , wherein the colchicine is administered at 0.5 mg.

20. The method according to claim 8 , wherein the colchicine is administered at 0.5 mg.

21. The method according to claim 9 , wherein the colchicine is administered at 0.5 mg.

22. The method according to claim 10 , wherein the colchicine is administered at 0.5 mg.

23. The method according to claim 11 , wherein the colchicine is administered at 0.5 mg.

24. The method according to claim 1 , wherein the colchicine is administered once, twice or three times a day.

25. The method according to claim 24 , wherein the coichicine is administered once per day.

26. The method according to claim 1 , wherein the patient is an adult human.

27. A method of reducing the risk of a stroke in a patient after having an MI, the method comprising initiating the administration of colchicine at a daily low dose to the patient within about 30 days of an MI.

28. The method according to claim 27 , wherein the method comprises administering coichicine within 4 to 7 days of the MI.

29. The method according to claim 27 , wherein the patient was prescribed a medication.

30. The method according to claim 29 , wherein the medication is an antiplatelet agent.

31. The method according to claim 29 , wherein the medication is aspirin.

32. The method according to claim 29 , wherein the medication is a statin.

33. The method according to claim 27 , wherein the patient has atherosclerotic coronary artery disease.

34. The method according to claim 27 , wherein the coichicine is administered at 0.5 mg.

35. The method according to claim 27 , wherein the colchicine is administered once per day.

36. The method according to claim 27 , wherein the administration of colchicine is initiated upon assessment in (a) an emergency department (ED), (b) the hospital, or (c) a medical office setting.

37. The method according to claim 27 , wherein the colchicine is in the form of a coated tablet.

38. The method of claim 37 , wherein the tablet is film-coated.

39. The method of claim 27 , wherein the patient is an adult human.

40. The method according to claim 8 , wherein the patient was prescribed a medication.

41. The method according to claim 40 , wherein the medication is an antiplatelet agent.

42. The method according to claim 40 , wherein the medication is aspirin.

43. The method according to claim 40 , wherein the medication is a statin.

44. The method according to claim 8 , wherein the patient has atherosclerotic coronary artery disease.

45. The method according to claim 8 , wherein the colchicine is administered once per day.

46. The method according to claim 8 , wherein the administration of colchicine is initiated upon assessment in (a) an emergency department (ED), (b) the hospital, or (c) a medical office setting.

47. The method according to claim 8 , wherein the colchicine is in the form of a coated tablet.

48. The method of claim 47 , wherein the tablet is film-coated.

49. The method of claim 8 , wherein the patient is an adult human.

50. The method of claim 8 , wherein the cardiovascular event is resuscitated cardiac arrest.