Controllable ocular phototherapy
Embodiments of the present disclosure are directed to a wearable phototherapy eye device. In an example, phototherapy can be controlled by varying an emission property of light emitted from the wearable phototherapy eye device to a user eye. In particular, the wearable phototherapy eye device includes a light source oriented to emit the light towards the user eye. The wearable phototherapy eye device also includes controls, such as electrical, mechanical, and/or electro-mechanical controls, to vary the emission property of the light based on an emission target associated with a sleep phase.
1. A phototherapy lens comprising:
a lens body comprising:
a silicone top layer; and
a rigid gas permeable (RGP) bottom layer configured to conform to an eye of a subject and affixed to the top layer to form a gap between the top and bottom layers;
wherein the lens body has a transparent optical zone and a periphery outside of the transparent optical zone;
a light source disposed within the transparent optical zone or the periphery and configured to emit light towards a user side of the lens body;
a controller disposed within the lens body, electrically coupled with the light source, and configured to vary an emission property of the light;
a receiving coil disposed within the periphery and configured to induce electrical current based on a wireless power transmission from a transmission coil; and
a converter disposed within the lens body and configured to convert the induced electrical current into a converted electrical current, wherein power to the controller is available based on the converted electrical current.
2. The phototherapy lens of claim 1 , wherein the transparent optical zone has a circular shape defined by a radius of at least 3.5 mm, and wherein the light source is positioned within an inner circle of the circular shape having a radius of less than 2 mm.
3. The phototherapy lens of claim 1 , wherein the light source comprises a light emitting diode, wherein a side of the light emitting diode opposite to the user side is opaque to the light.
4. The phototherapy lens of claim 1 , wherein the lens body comprises an orthokeratology lens.
5. The phototherapy lens of claim 1 , wherein the gap comprises an oxygen permeable material.
6. The phototherapy lens of claim 1 , wherein the light source comprises a coating of an oxygen permeable material.
7. The phototherapy lens of claim 1 , wherein the gap is uniformly distributed within the lens body.
8. The phototherapy lens of claim 1 , wherein each of the bottom layer and the top layer has a thickness between 10 μm and 100 μm, and wherein the gap separates the bottom layer and the top layer by a separation between 100 μm and 1000 μm.
9. The phototherapy lens of claim 1 , wherein the controller is configured to vary the emission property of the light based on an emission target associated with a sleep phase.
10. The phototherapy lens of claim 9 , wherein the emission property is varied further based on a predetermined transfer function of the light from the phototherapy lens to an eye retina, the predetermined transfer function being defined based on a response to an electroretinogram (ERG) or an electrooculogram (EOG).
11. The phototherapy lens of claim 10 , further comprising a set of electrodes configured to measure an electroretinogram (ERG) response of the eye retina at different light emission levels.
12. The phototherapy lens of claim 11 , further comprising a memory integrated into the phototherapy lens for storing computer-readable instructions.
13. The phototherapy lens of claim 1 , further comprising an external power source with at least one or more transmission coils for wireless power transmission to the receiving coil.
14. The phototherapy lens of claim 1 , further comprising an internal power source.
15. A phototherapy lens comprising:
a lens body comprising:
a silicone top layer; and
a rigid gas permeable (RGP) bottom layer configured to conform to an eye of a subject;
wherein the lens body has a transparent optical zone and a periphery outside of the transparent optical zone;
a light source disposed within the lens body;
a set of electrodes disposed within the lens body, the set of electrodes configured to measure an electroretinogram (ERG) response or an electrooculogram (EOG) response of the eye; and
a controller disposed within the lens body, electrically coupled with the light source, and configured to vary an emission property of the light source based on calibration levels derived from the ERG or EOG response.
16. The phototherapy lens of claim 15 , wherein the lens body comprises an orthokeratology lens.
17. The phototherapy lens of claim 15 , wherein the light source comprises a coating of an oxygen permeable material.
18. The phototherapy lens of claim 15 , wherein a gap is uniformly distributed within the lens body.
19. The phototherapy lens of claim 15 , wherein the controller is configured to vary the emission property of the light source based on an emission target associated with a sleep phase.