Drug delivery device
There is described a patch pump comprising a cartridge, a power source, a pump system, a drug delivery device and a control system configured to operate in particular the pump system and the drug delivery device. The pump system comprises, on the one hand, a pump having a pump housing containing a pump piston and a valve piston and, on the other hand, a pump drive comprising a piston motor and a valve motor for driving the pump piston and the valve piston independently from each other through a first and a second transmission. The drug delivery device comprises a transdermal delivery system having a needle actuation mechanism configured for transdermal insertion of a cannula.
1. A drug delivery device comprising:
a transdermal delivery system having a needle actuation mechanism and a needle assembly comprising:
a needle connected to a needle holder,
a cannula connected to a cannula holder, and
a needle guiding element configured to guide axial displacement of the needle and the cannula,
the needle actuation mechanism comprising:
a cam member having a cam housing and
a spring housed inside the cam housing in order to impart rotational movement to the cam member relative to the needle guiding element, said needle and cannula holders comprising each an engagement portion,
wherein the engagement portion of the needle holder is configured to engage with a first and a second cam surface and the engagement portion of the cannula holder is configured to engage with a locking surface, the first and second cam surfaces being arranged around a circumference of an outer surface of the cam housing along a first portion with a first gradient configured for a needle insertion movement followed by a second portion with a second gradient configured for a needle retraction movement such that the needle and the cannula are moved from a retracted position to an extended position upon rotation of the cam member through a first predetermined angle, and such that the needle is brought back in the retracted position upon further rotation of said cam member through a second predetermined angle, whereby during rotation through said second predetermined angle, the engagement portion of the cannula holder abuts against the locking surface to maintain the cannula in the extended position configured for transdermal delivery.
2. The drug delivery device according to claim 1 , wherein said first and second cam surfaces correspond to each side of a needle holder guide disposed around said circumference of the outer surface of the cam housing.
3. The drug delivery device according to claim 2 , wherein the needle holder guide is a projecting part or a groove.
4. The drug delivery device according to claim 1 , wherein in a position prior to use, the cam member is engaged with a cam engaging element to prevent rotation of the cam member, said delivery system further comprising a needle insertion release mechanism configured to disengage the cam engaging element to enable rotation of the cam member caused by the spring.
5. The drug delivery device according to claim 1 , wherein the needle guiding element comprises a needle housing for sliding movement of the needle and cannula holders inside the needle housing, wherein a shape of a transversal cross-section of the needle housing corresponds to a shape of a transversal cross-section of the needle and cannula holders.
6. The drug delivery device according to claim 1 , wherein the needle holder is mounted on top of the cannula holder and cooperates with the needle guiding element to ensure axial displacement of the needle and the cannula upon rotation of the cam member, wherein the cannula holder comprises a through hole for receiving the needle.
7. The drug delivery device according to claim 6 , wherein the cannula holder comprises an inlet aperture for receiving an inlet tube, and an inlet channel extending from the inlet aperture to said through hole, the needle being adapted to perform a function of sealing between the inlet channel and the cannula to avoid any leakage prior to use of the delivery system.
8. The drug delivery device according to claim 7 , wherein the inlet aperture of the cannula holder is configured to be in fluid communication with the cannula once the needle is moved back in the retracted position after actuation of the needle actuation mechanism of the transdermal delivery system.