Implantable compositions having fibers and methods of making and using them

1. An implantable composition comprising a first set of fibers and a second set of fibers, the first set of fibers manufactured to have a first binding surface, the second set of fibers manufactured to have a second binding surface, the first binding surface of the first set of fibers configured to bind at least at or near the second binding surface of the second set of fibers and the second set of fibers configured to bind at least at or near the first binding surface of the first set of fibers, wherein the first set of fibers comprises a body portion and an end portion such that the first binding surface of the first set of fibers is disposed near the end portion.

2. The implantable composition according to claim 1 , wherein the first set of fibers comprises a first non-binding surface and the second set of fibers comprises a second non-binding surface, wherein the first binding surface of the first set of fibers bind at least at or near the second binding surface of the second set of fibers and the second set of fibers bind at least at or near the first binding surface of the first set of fibers so as to form a coherent mass of bond first set of fibers and second set of fibers.

3. The implantable composition according to claim 1 , wherein the first binding surface of the first set of fibers comprises a curl portion, a hook portion, a branched portion, a barbed portion, a looped portion, a chain portion, a helical portion, a spiral portion, an angular portion, a twist portion, a ribbon portion, a sinusoidal portion, or a zigzag portion and the second binding surface of the second set of fibers also comprises a curl portion, a hook portion, a branched portion, a barbed portion, a looped portion, a chain portion, a helical portion, a spiral portion, an angular portion, a twist portion, a ribbon portion, a sinusoidal portion, or a zigzag portion.

4. The implantable composition according to claim 2 , wherein the first non-binding surface of the first set of fibers comprises a straight portion and the second non-binding surface of the second set of fibers also comprises a straight portion and the implantable composition is a bone void filler.

5. The implantable composition according to claim 1 , wherein the first set of fibers and the second set of fibers comprise a resorbable polymer, a non-resorbable polymer, an ink of organic material, an ink of synthetic material, a therapeutic agent, a soft tissue, a bone material or a combination thereof.

6. The implantable composition according to claim 1 , wherein the first set of fibers and the second set of fibers comprise bone material disposed in or on the fibers.

7. The implantable composition according to claim 1 , wherein the first set of fibers and the second set of fibers are configured to be molded into a putty, paste or pre-formed shape, or are configured to be lyophilized.

8. The implantable composition according to claim 1 , wherein the first set of fibers and the second set of fibers are made by additive manufacturing, stereolithography, extrusion molding, ultraviolet light printing or a combination thereof.

9. A computer implemented method for producing an implantable composition, the method comprising generating a 3-D digital model of the implantable composition, the 3-D digital model being of a first set of fibers and a second set of fibers, the first set of fibers comprising a first binding surface, the second set of fibers comprising a second binding surface, the first binding surface of the first set of fibers configured to bind at least at or near the second binding surface of the second set of fibers and the second set of fibers configured to bind at least at or near the first binding surface of the first set of fibers, wherein the first set of fibers comprises a body portion and an end portion such that the first binding surface of the first set of fibers is disposed near the end portion; and storing the 3-D digital model on a database coupled to a processor, the processor having instructions for selecting the implant material based on the stored 3-D digital model and for instructing a print surface of a 3-D printer to print the implantable composition on the print surface.

10. The computer implemented method of claim 9 , wherein the first binding surface of the first set of fibers comprises a curl portion, a hook portion, a branched portion, a barbed portion, a looped portion, a chain portion, a helical portion, a spiral portion, an angular portion, a twist portion, a ribbon portion, a sinusoidal portion, or a zigzag portion and the second binding surface of the second set of fibers also comprises a curl portion, a hook portion, a branched portion, a barbed portion, a looped portion, a chain portion, a helical portion, a spiral portion, an angular portion, a twist portion, a ribbon portion, a sinusoidal portion, or a zigzag portion.

11. The computer implemented method of claim 9 , wherein the first set of fibers comprises a first non-binding surface and the second set of fibers comprises a second non-binding surface.

12. The computer implemented method according to claim 9 , wherein the first set of fibers and the second set of fibers comprise a resorbable polymer, a non-resorbable polymer, an ink of organic material, an ink of synthetic material, a therapeutic agent, a soft tissue, a bone material or a combination thereof, wherein the first set of fibers and the second set of fibers comprise bone material disposed in or on the fibers.

13. The computer implemented method according to claim 11 , wherein the first non-binding surface of the first set of fibers comprises a straight portion and the second non-binding surface of the second set of fibers also comprises a straight portion and the implantable composition is a bone void filler.

14. The computer implemented method according to claim 9 , wherein the first set of fibers and the second set of fibers are configured to be molded into a putty, paste or are configured to be lyophilized.

15. The computer implemented method according to claim 9 , wherein before the 3-D digital model of the implantable composition is generated, a 3-D digital model of an intended tissue repair site is generated, and the 3-D digital model of the implantable composition is generated to fit within the 3-D digital model of the tissue repair site.

16. The computer implemented method according to claim 9 , wherein before the 3-D digital model of the implantable composition is generated, a type of material that the 3-D digital model of the implantable composition is made from is selected.

17. A method of treating a bone or soft tissue defect, the method comprising inserting an implantable composition into the bone or soft tissue defect, the implantable composition comprising a first set of fibers and a second set of fibers, the first set of fibers manufactured to have a first binding surface, the second set of fibers manufactured to have a second binding surface, the first binding surface of the first set of fibers bound to at least at or near the second binding surface of the second set of fibers and the second set of fibers bound to at least at or near the first binding surface of the first set of fibers, wherein the first set of fibers comprises a body portion and an end portion such that the first binding surface of the first set of fibers is disposed near the end portion.

18. The method of treating according to claim 17 , wherein the first binding surface of the first set of fibers comprises a curl portion, a hook portion, a branched portion, a barbed portion, a looped portion, a chain portion, a helical portion, a spiral portion, an angular portion, a twist portion, a ribbon portion, a sinusoidal portion, or a zigzag portion and the second binding surface of the second set of fibers also comprises a curl portion, a hook portion, a branched portion, a barbed portion, a looped portion, a chain portion, a helical portion, a spiral portion, an angular portion, a twist portion, a ribbon portion, a sinusoidal portion, or a zigzag portion.

19. The method of treating according to claim 17 , wherein the first set of fibers comprises a first non-binding surface and the second set of fibers comprises a second non-binding surface, and the implantable composition is a bone void filler.

20. The implantable composition according to claim 2 , wherein the first non-binding surface of the first set of fibers is disposed near the body portion.