Methylphosphinic acid compositions and methods for reducing aging
A composition that includes methylphosphinic acid or a salt thereof, and optionally methylphosphonic acid or a salt thereof, and an ingredient acceptable for consumption by a mammal is provided herein. Also provided is a method for reducing aging in a mammal that involves providing or administering methylphosphinic acid or a salt thereof, and optionally, methylphosphonic acid or a salt thereof, to the mammal in need thereof for consumption. A composition for use in such a method and an article useful for such a method include those in the form of a food product such as a prepackaged or processed food or meal, a beverage, a nutritional supplement, or a nutraceutical.
1. A composition comprising methylphosphinic acid or a salt thereof and a pharmaceutically acceptable ingredient.
2. The composition of claim 1 , which is a liquid, wherein the methylphosphinic acid or a salt thereof is at a concentration of about 2 mg/L to about 600 mg/L.
3. The composition of claim 2 , which is a beverage, wherein the methylphosphinic acid or a salt thereof is at a concentration of about 0.005 mg/L to about 1 mg/L.
4. The composition of claim 3 , further comprising methylphosphonic acid or a salt thereof.
5. The composition of claim 4 , which comprises about equal amounts of (a) the methylphosphinic acid or a salt thereof, and (b) the methylphosphonic acid or a salt thereof.
6. The composition of claim 1 , which is a solid that comprises about 0.3 mg to about 2 g of the methylphosphinic acid or a salt thereof per kilogram of the solid.
7. The composition of claim 1 , which is prepackage food that comprises about 0.01 mg to about 5 mg of the methylphosphinic acid or a salt thereof per kilogram of the prepackaged food.
8. The composition of claim 7 , further comprising methylphosphonic acid or a salt thereof.
9. The composition of claim 8 , which comprises about equal amounts of (a) the methylphosphinic acid or a salt thereof, and (b) the methylphosphonic acid or a salt thereof.
10. The composition of claim 6 , which is a powder that comprises about 1 mg/kg to about 2 g/kg of the methylphosphinic acid or a salt thereof.
11. A method for reducing aging in a mammal in need thereof, the method comprising administering the composition of claim 1 to the mammal.
12. A composition consisting essentially of methylphosphinic acid or a salt thereof and one or more pharmaceutically acceptable ingredients.
13. The composition of claim 12 , which further includes methylphosphonic acid or a salt thereof.
14. The composition of claim 12 , which is a liquid consisting essentially of about 0.005 mg/L to about 600 mg/L of the methylphosphinic acid or a salt thereof.
15. The composition of claim 12 , which is a solid consisting essentially of about 0.01 mg/kg to about 2 g/kg of the methylphosphinic acid or a salt thereof.
16. A method for reducing aging in a mammal in need thereof, the method comprising administering the composition of claim 12 to the mammal.