IP Library Granted Patent US 11,458,336
Granted Patent B2
US 11,458,336 · App. 16/798,644 · Granted Oct 4, 2022

Neutron capture therapy system comprising a beam shaping assembly configured to shape a neutron beam

Inventors: Chiung-Wen Tsai (Jiangsu, CN); Weilin Chen (Jiangsu, CN); Ming-Chen Hsiao (Jiangsu, CN); Yuanhao Liu (Jiangsu, CN)
Assignee: NEUBORON MEDTECH LTD.
A61N5/1077A61N5/10A61N5/1048A61N5/1064A61N5/1065A61N5/1067A61N5/1071A61N5/1078G21G4/00G21G4/02G21K1/02G21K1/025A61N2005/109A61N2005/1012A61N2005/1085A61N2005/1094
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Quick Facts
Patent No.
US 11,458,336
App. No.
16/798,644
Granted
Oct 4, 2022
Kind
B2
Abstract

A neutron capture therapy system includes an accelerator for generating a charged particle beam, a neutron generator for generating a neutron beam having neutrons after irradiation by the charged particle beam, and a beam shaping assembly for shaping the neutron beam. The beam shaping assembly includes a moderator and a reflecting assembly surrounding the moderator. The neutron generator generates the neutrons after irradiation by the charged particle beam. The moderator moderates the neutrons generated by the neutron generator to a preset energy spectrum. The reflecting assembly includes a plurality of reflectors configured to guide deflected neutrons back to the neutron beam and a supporting member to support the plurality of reflectors. A lead-antimony alloy is for the reflecting assembly to mitigate a creep effect that occurs when only a lead material is for the plurality of reflectors, thereby improving the structural strength of a beam shaping assembly.

Claims (28)

1. A neutron capture therapy system, comprising:

an accelerator configured to generate a charged particle beam;

a neutron generator configured to generate a neutron beam having neutrons after an irradiation by the charged particle beam; and

a beam shaping assembly configured to shape the neutron beam, wherein the beam shaping assembly comprises a moderator configured to moderate the neutron beam generated by the neutron generator to a preset energy spectrum and a reflecting assembly surrounding the moderator;

wherein the reflecting assembly comprises a plurality of reflectors configured to guide deflected neutrons back to the neutron beam to increase an intensity of the neutron beam in the preset energy spectrum and a supporting member configured to hold the plurality of reflectors.

2. The neutron capture therapy system according to claim 1 , wherein the reflecting assembly further comprises a plurality of cells correspondingly forming a plurality of cores, each of the plurality of cells forms one of the plurality of cores, the plurality of cores have a plurality of accommodating spaces, each of the plurality of cores has a corresponding accommodating space of the plurality of accommodating spaces, the plurality of reflectors are correspondingly disposed in the plurality of accommodating spaces of the plurality of cores, and the plurality of cores are connected to form the supporting member.

3. The neutron capture therapy system according to claim 2 , wherein the supporting member is integrally formed, and the plurality of reflectors comprise a material disposed in the plurality of accommodating spaces of the plurality of cores.

4. The neutron capture therapy system according to claim 2 , wherein the reflecting assembly further includes a top plate, a bottom plate disposed opposite to the top plate, and side plates connecting to the top plate and the bottom plate and surrounding the plurality of cores, wherein the plurality of cores, the plurality of reflectors disposed in the plurality of accommodating spaces of the plurality of cores, the top plate, the bottom plate, and the side plates correspondingly form a reflecting module.

5. The neutron capture therapy system according to claim 4 , wherein the plurality of cores, the top plate, the bottom plate, and the side plates comprise a material with a low neutron absorption cross section and a low activity with neutrons, and a proportion of a total volume of the plurality of cores, the top plate, the bottom plate, and the side plates in a volume of the plurality of reflectors is less than 10%.

6. The neutron capture therapy system according to claim 5 , wherein the plurality of reflectors comprise lead, and the plurality of cores, the top plate, the bottom plate, and the side plates comprise lead-antimony alloy.

7. The neutron capture therapy system according to claim 6 , wherein an equivalent total antimony content in the lead-antimony alloy is less than 1%.

8. A neutron capture therapy system, comprising:

a beam shaping assembly configured to shape a neutron beam having neutrons, wherein the beam shaping assembly comprises a moderator configured to moderate the neutron beam to a preset energy spectrum, a reflecting assembly surrounding the moderator, and a shielding assembly surrounding the reflecting assembly;

wherein the shielding assembly comprises a supporting member configured to hold the reflecting assembly and a plurality of shieldings arranged in the supporting member.

9. The neutron capture therapy system according to claim 8 , wherein the shielding assembly further comprises a plurality of cells correspondingly forming a plurality of cores, each of the plurality of cells forms one of the plurality of cores, the plurality of cores have a plurality of accommodating spaces, each of the plurality of cores has a corresponding accommodating space of the plurality of accommodating spaces, the plurality of shieldings are correspondingly disposed in the plurality of accommodating spaces of the plurality of cores, and the plurality of cores are connected to form the supporting member.

10. The neutron capture therapy system according to claim 9 , wherein a cross section of each of the plurality of cores is a hexagon.

11. The neutron capture therapy system according to claim 9 , wherein the supporting member is integrally formed, and the plurality of shieldings comprise a material disposed in the plurality of accommodating spaces of the plurality of cores.

12. The neutron capture therapy system according to claim 9 , wherein the reflecting assembly further includes a top plate, a bottom plate disposed opposite to the top plate, and side plates connecting to the top plate and the bottom plate and surrounding the plurality of cores provided outside the supporting member, wherein the plurality of cores, the plurality of shieldings disposed in the plurality of cores, the top plate, the bottom plate, and the side plates correspondingly form a shielding module.

13. The neutron capture therapy system according to claim 9 , wherein the plurality of shieldings comprise lead, and wherein the plurality of cores, the top plate, the bottom plate, and the side plates comprise a material with a low neutron absorption cross section and a low activity with neutrons.

14. The neutron capture therapy system according to claim 13 , wherein a proportion of a total volume of the plurality of cores, the top plate, the bottom plate, and the side plates in a volume of the plurality of shieldings is less than 10%.

15. The neutron capture therapy system according to claim 8 , wherein the reflecting assembly comprises a plurality of reflectors configured to guide deflected neutrons back to the neutron beam to increase an intensity of the neutron beam in the preset energy spectrum, and the supporting member configured to support the plurality of reflectors, the plurality of reflectors comprise lead, and the supporting member comprises aluminum alloy or lead-antimony alloy.

16. A neutron capture therapy system, comprising:

a beam shaping assembly configured to shape a neutron beam having neutrons, wherein the beam shaping assembly comprises a moderator configured to moderate the neutron beam to a preset energy spectrum and a reflecting assembly surrounding the moderator;

wherein the reflecting assembly comprises a plurality of reflectors configured to guide deflected neutrons back to the neutron beam to increase an intensity of the neutron beam in the preset energy spectrum and a plurality of cells configured to support the plurality of reflectors, the plurality of cells correspondingly form a plurality of cores, each of the plurality of cells forms one of the plurality of cores, each of the plurality of cores has an accommodating space, the accommodating space is configured to receive one of the plurality of reflectors or to receive a material configured to form a shielding, and the shielding is configured to shield the neutrons.

17. The neutron capture therapy system according to claim 16 , wherein the plurality of cores are connected to form a supporting member, the reflecting assembly further includes a top plate, a bottom plate disposed opposite to the top plate, and side plates connecting to the top plate and the bottom plate and surrounding the plurality of cores provided outside the supporting member.

18. The neutron capture therapy system according to claim 17 , wherein the plurality of cores, the top plate, the bottom plate, and the side plates comprises a material with a low neutron absorption cross section and a low activity with neutrons, and a proportion of a total volume of the plurality of cores, the top plate, the bottom plate, and the side plates in a volume of the plurality of reflectors is less than 10%.

19. The neutron capture therapy system according to claim 16 , wherein the plurality of cores are connected to form a supporting member, the supporting member is integrally formed, and the shielding comprises the material deposited in the accommodating space.

20. The neutron capture therapy system according to claim 16 , wherein the plurality of cores are connected to form a supporting member, the material in the accommodating space comprises lead, and the supporting member comprises aluminum alloy or lead-antimony alloy.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 24, 2020
From: TSAI, CHIUNG-WEN; CHEN, WEILIN; HSIAO, MING-CHEN; LIU, YUANHAO
To: NEUBORON MEDTECH LTD.
Reel/Frame 051899/0515 →
Priority Claims (2)
CN 201710733144.1 · Aug 24, 2017 · national
CN 201721063911.4 · Aug 24, 2017 · national
Continuity (2)
Continuation PCTCN2018100572 · Aug 15, 2018
Related Publication 20200206538A1 · Jul 2, 2020
Cited By (4)
US 12,303,713 US 12,434,074 US 12,447,359 US 12,465,786