IP Library › Granted Patent US 11,464,718
Granted Patent B2
US 11,464,718 · App. 15/684,226 · Granted Oct 11, 2022

Oral care compositions

Inventors: Aarti Rege (East Windsor, NJ); Luciana Rinaudi Marron (Somerset, NJ)
Assignee: Colgate-Palmolive Company
A61K8/27A61K8/21A61K8/24A61K8/365A61K8/42A61Q11/00A61K2800/28A61K2800/30A61K2800/48
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Quick Facts
Patent No.
US 11,464,718
App. No.
15/684,226
Granted
Oct 11, 2022
Kind
B2
Abstract

An oral care composition comprising zinc phosphate, stannous fluoride and a salicylamide, as well as methods of using the same.

Claims (14)

1. A high water oral care composition comprising an orally acceptable carrier, zinc phosphate hydrate, stannous fluoride, and a salicylamide, wherein the salicylamide has the formula:

wherein R 1 is H and R 2 is H;

wherein the amount of salicylamide is 0.1% by weight, relative to the composition;

wherein the amount of zinc phosphate hydrate is 1% by weight, relative to the composition.

2. The composition of claim 1 wherein the zinc phosphate is a preformed salt of zinc phosphate.

3. The composition of claim 1 wherein the salicylamide is present in an antibacterially-effective amount or an anti-plaque effective amount.

4. The composition of claim 1 wherein the amount of water in the high water oral care composition is 10% by weight or more, relative to the weight of the oral care composition.

5. The composition of claim 1 further comprising an organic buffer system.

6. The composition of claim 1 , further comprising one or more humectants.

7. The composition of claim 1 , further comprising an effective amount of one or more alkali phosphate salts.

8. The composition of claim 1 wherein the oral care composition is a dentifrice.

9. The composition of claim 1 wherein the composition does not contain any halogenated biphenyl ether antibacterial agents.

10. A method of treatment or prevention of erosive tooth demineralization, gingivitis, plaque, and/or dental caries, the method comprising the application to the oral cavity of a person in need thereof a composition according to claim 1 .

11. A method to (i) reduce or inhibit formation of dental caries, (ii) reduce, repair or inhibit pre-carious lesions of the enamel, (iii) reduce or inhibit demineralization and promote remineralization of the teeth, (iv) reduce hypersensitivity of the teeth, (v) reduce or inhibit gingivitis, (vi) promote healing of sores or cuts in the mouth, (vii) reduce levels of acid producing bacteria, (viii) to increase relative levels of arginolytic bacteria, (ix) inhibit microbial biofilm formation in the oral cavity, (x) raise and/or maintain plaque pH at levels of at least pH 5.5 following sugar challenge, (xi) reduce plaque accumulation, (xii) treat, relieve or reduce dry mouth, (xiii) clean the teeth and oral cavity (xiv) reduce erosion, (xv) prevents stains and/or whiten teeth, (xvi) immunize the teeth against cariogenic bacteria; and/or (xvii) promote systemic health, including cardiovascular health, comprising the application to the oral cavity of a person in need thereof a composition according to claim 1 .

Continuity (2)
Provisional Application 62437104 · Dec 21, 2016
Related Publication 20180168964A1 · Jun 21, 2018