Microcatheter

1. A method for producing a microcatheter comprising an inner layer, a strike layer and an outer layer and a braided skeleton located between the inner layer and the strike layer, the method comprising:

providing a mandrel coated with Polytetrafluoroethylene (PTFE), thereby forming an inner layer, and a strike layer; applying a braided skeleton or coil on the mandrel;

applying a polycarbonate-based thermoplastic polyurethane sleeve on the PTFE and strike layers, thereby forming an outer layer;

applying a heat shrink sleeve on the polycarbonate-based thermoplastic polyurethane sleeve;

applying heat and/or pressure on the heat shrink layer sleeve, thereby causing at least the outer layer to intercalate on and/or into the braid;

peeling off the heat shrink sleeve;

removing the mandrel.

2. The method of claim 1 , wherein the inner layer has a thickness of 0.0015 inch or less, wherein the strike layer comprises a polyether block amide and has a thickness of 0.001 inch or less, and wherein at least a portion of the polycarbonate-based thermoplastic polyurethane sleeve has a shore of 90A or below.

3. The method of claim 2 , wherein the polyether block amide of the strike layer has a shore of about 55D.

4. The method of claim 1 , wherein the braided skeleton has a wire arrangement of 130 Picks Per Inch (PPI).

5. The method of claim 1 , wherein the polycarbonate-based thermoplastic polyurethane sleeve comprises a distal portion comprising a first distal section and a second distal section, wherein the first distal section is distal to the second distal section and wherein the first distal section has a lower shore than the second distal section.

6. The method of claim 5 , wherein the first distal section has a shore of 80A or below and the second distal section has a shore of 90A or below.

7. The method of claim 5 , wherein the polycarbonate-based thermoplastic polyurethane sleeve comprises an intermediary portion comprising at least a first intermediary section and a second intermediary section, wherein the first intermediary section is distal to the second intermediary section and wherein said first intermediary section has a lower shore than that of the second intermediary section.

8. The method of claim 7 , wherein the intermediary portion further comprises a third intermediary section, wherein the third intermediary section is proximal to the second intermediary section and wherein the third intermediary section has a higher shore than the second and first intermediary sections.

9. The method of claim 8 , wherein the first intermediary section is made of a polyether block amide having a shore of about 40D.

10. The method of claim 9 , wherein the second intermediary section is made of a polyether block amide having a shore of about 55D.

11. The method of claim 10 , wherein the third intermediary section is made of a polyether block amide having a shore of about 60D.

12. The method of claim 8 , wherein the intermediary portion has a length of 400 mm or below.

13. The method of claim 5 , wherein the outer layer further comprises a proximal portion, wherein the proximal portion of the outer layer is made of a polyether block amide having a shore of above 65D.

14. The method of claim 1 , wherein the microcatheter has an inner diameter of 0.50-0.7 mm and outer diameter of 0.8-0.9 mm at its distal end and 0.8-1.0 mm at its proximal end, and an active length in the range of 105 to 175 cm.