Left atrial appendage closure device with anti-thrombogenic covering

1. A left atrial appendage device, comprising:

an expandable frame configured to shift between a first configuration and an expanded configuration;

a fabric mesh disposed along at least a portion of the expandable frame;

an anti-thrombogenic coating disposed along the fabric mesh;

wherein the fabric mesh includes a plurality of filaments;

wherein the plurality of filaments are arranged into a fiber bundle; and

wherein the anti-thrombogenic coating migrates to an interior region of the fiber bundle.

2. The left atrial appendage device of claim 1 , wherein the plurality of filaments include polyethylene terephthalate.

3. The left atrial appendage device of claim 1 , wherein the plurality of filaments include polyester.

4. The left atrial appendage device of claim 1 , wherein the anti-thrombogenic coating encapsulates at least some of the plurality of filaments.

5. The left atrial appendage device of claim 1 , wherein the anti-thrombogenic coating individually coats each of the plurality of filaments.

6. The left atrial appendage device of claim 1 , wherein the plurality of filaments are arranged in a non-woven configuration.

7. The left atrial appendage device of claim 1 , wherein the anti-thrombogenic coating includes a fluoropolymer.

8. The left atrial appendage device of claim 1 , wherein the anti-thrombogenic coating includes polyvinylidene fluoride.

9. The left atrial appendage device of claim 1 , wherein the anti-thrombogenic coating includes a polyvinylidene fluoride copolymer.

10. The left atrial appendage device of claim 1 , wherein the anti-thrombogenic coating includes poly(vinylidene fluoride-co-hexafluoropropylene).

11. The left atrial appendage device of claim 1 , wherein the anti-thrombogenic coating includes poly[bis (trifluoroethoxy)phosphazene].

12. A left atrial appendage device, comprising: an expandable framework configured to shift between a delivery configuration and a deployed configuration; wherein the expandable framework is configured to engage a left atrial appendage when in the deployed configuration; a fabric disposed along at least a portion of the expandable framework, the fabric including one or more knitted fiber bundles; wherein each of the one or more knitted fiber bundles include a plurality of filaments; and an anti-thrombogenic coating disposed along each of the plurality of filaments that migrates to an interior region of the knitted fiber bundle.

13. The left atrial appendage device of claim 12 , wherein the anti-thrombogenic coating encapsulates each of the plurality of filaments.

14. The left atrial appendage device of claim 12 , wherein the anti-thrombogenic coating includes a fluoropolymer.

15. The left atrial appendage device of claim 12 , wherein the anti-thrombogenic coating includes poly(vinylidene fluoride-co-hexafluoropropylene).

16. An occlusive medical device, comprising: an expandable frame configured to shift between a delivery configuration and an expanded configuration; wherein the expandable frame is configured to be implanted adjacent to a left atrial appendage; a fabric mesh disposed along at least a portion of the expandable frame, the fabric mesh including one or more fiber bundles arranged into a pattern; wherein each of the one or more fiber bundles include a plurality of filaments; an anti-thrombogenic coating disposed along each of the plurality of filaments that migrates to an interior region of the one or more fiber bundles; and wherein at least one of the one or more fiber bundles includes an interior region and wherein a section of the anti-thrombogenic coating is disposed along the interior region.

17. The occlusive medical device of claim 16 , wherein the anti-thrombogenic coating encapsulates each of the plurality of filaments.