IP Library › Granted Patent US 11,492,365
Granted Patent B2
US 11,492,365 · App. 17/571,351 · Granted Nov 8, 2022

Heterocyclic GLP-1 agonists

Inventors: Qinghua Meng (Shanghai, CH); Xichen Lin (Shanghai, CN); Haizhen Zhang (Shanghai, CN); Hui Lei (Shanghai, CN); Andrew Jennings (San Francisco, CA)
Assignee: GASHERBRUM BIO, INC.
C07F9/6561
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Quick Facts
Patent No.
US 11,492,365
App. No.
17/571,351
Granted
Nov 8, 2022
Kind
B2
Abstract

This disclosure relates to GLP-1 agonists of Formula (I): including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.

Claims (20)

1. A compound which is:

or a pharmaceutically acceptable salt thereof.

2. A compound which is:

3. A pharmaceutical composition comprising the compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.

4. A compound which is:

or a pharmaceutically acceptable salt thereof.

5. A compound which is:

6. A pharmaceutical composition comprising the compound of claim 4 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.

7. A compound which is:

or a pharmaceutically acceptable salt thereof.

8. A compound which is:

9. A pharmaceutical composition comprising the compound of claim 7 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.

10. A compound which is:

or a pharmaceutically acceptable salt thereof.

11. A compound which is:

12. A pharmaceutical composition comprising the compound of claim 10 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.

13. A compound which is:

or a pharmaceutically acceptable salt thereof.

14. A compound which is:

15. A pharmaceutical composition comprising the compound of claim 13 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE 5TH INVENTOR'S LAST NAME PREVIOUSLY RECORDED ON REEL 059947 FRAME 0757. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jun 8, 2022
From: MENG, QINGHUA; LIN, XICHEN; ZHANG, HAIZHEN; XING, WEIQIANG; LEI, HUI
To: SHANGHAI SHOUTI BIOTECHNOLOGY CO., LTD.
Reel/Frame 060313/0905 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 18, 2022
From: MENG, QINGHUA; LIN, XICHEN; ZHANG, HAIZHEN; XING, WEIQIANG; HUI, HUI
To: SHANGHAI SHOUTI BIOTECHNOLOGY CO., LTD.
Reel/Frame 059947/0757 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 18, 2022
From: SHANGHAI SHOUTI BIOTECHNOLOGY CO., LTD.
To: GASHERBRUM BIO, INC.
Reel/Frame 059947/0855 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 18, 2022
From: JENNINGS, ANDREW
To: SHOUTI INC.
Reel/Frame 059947/0888 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 18, 2022
From: SHOUTI INC.
To: GASHERBRUM BIO, INC.
Reel/Frame 059947/0911 →
Priority Claims (2)
WO PCT/CN2020/074537 · Feb 7, 2020 · international
WO PCT/CN2020/109304 · Aug 14, 2020 · international
Continuity (2)
Continuation PCTCN2021075488 · Feb 5, 2021
Related Publication 20220213130A1 · Jul 7, 2022
Cited By (4)
US 50,455 US 12,291,529 US 12,595,264 US 12,747,233