Anti-rotation feature for infusion pump cartridge
Apparatus is described for administering a substance to a subject. A vial contains the substance and a stopper is disposed within the vial and is slidably coupled to the vial. A first threaded element is (a) rotatable with respect to the vial and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. At least a distal end of the second threaded element is substantially non-rotatable with respect to the vial, and the distal end of the second threaded element defines a coupling portion that couples the second threaded element to the stopper. The first threaded element, by rotating, linearly advances the stopper and at least the distal end of the second threaded element toward a distal end of the vial. Other embodiments are also described.
1. A method comprising:
threadedly coupling a first threaded element of a rotary drive to a second threaded element; and
receiving a proximal projection of a first cog of the rotary drive in a recess of a portion of a housing to impede linear movement of the first threaded element,
wherein a motor is configured to be powered by a battery, and a second cog attached to the motor is configured to be rotated about an axis to rotate said first cog and said first threaded element with respect to a vial to axially move said second threaded element relative to the first threaded element and to advance a stopper inside the vial.
2. The method of claim 1 , further comprising:
receiving a detected parameter from a sensor; and
controlling the motor with a control unit based on the detected parameter.
3. The method of claim 2 , wherein the sensor is configured to detect one or more physiological parameters of a subject.
4. The method of claim 3 , wherein said sensor is disposed externally to and spaced from said housing.
5. The method of claim 1 , further including advancing a plunger with said second threaded element.
6. The method of claim 1 , wherein the housing includes a base, and the portion of the housing is connected to the base.
7. The method of claim 1 , wherein the proximal projection of the first cog has an angled face.
8. An apparatus for administering a substance from a vial having a stopper slidably coupled within the vial, the apparatus comprising:
a housing configured to contain the vial with the vial extending along a first axis;
a first threaded component;
a first cog coupled to the first threaded component, the first cog having a proximal projection received in a recess of a portion of the housing to impede linear motion of the first threaded component;
a motor;
a battery configured to power the motor; and
a second cog configured to be selectively rotated by the motor about a second axis laterally spaced from the first axis,
wherein rotation of the second cog causes rotation of the first cog and the first threaded component about the first axis to linearly move the stopper through the vial and force the substance from the vial.
9. The apparatus of claim 8 , wherein the first threaded component is axially immobile with respect to the vial.
10. The apparatus of claim 9 , further comprising a second threaded component threadedly coupled to the first threaded component, wherein rotation of the first threaded component axially translates the second threaded component and the stopper.
11. The apparatus of claim 10 , wherein the second threaded component is rotationally fixed relative to the vial.
12. The apparatus of claim 8 , further comprising:
a cannula spaced from the vial and extending through the housing; and
a tube extending from the vial to the cannula that places the tube and cannula in fluid communication.
13. The apparatus of claim 8 , further comprising:
a control unit configured to control the motor; and
a sensor configured to provide the control unit with a detected parameter, wherein the control unit is configured to control the motor based on the detected parameter.
14. The apparatus of claim 13 , wherein the sensor is configured to detect one or more physiological parameters of a subject.
15. The apparatus of claim 14 , said sensor is disposed externally to and spaced from said housing.
16. The apparatus of claim 8 , wherein the housing comprises a housing top and a base coupled to the housing top, wherein the vial is configured to be attached to the base.
17. The apparatus of claim 16 , wherein the base defines a bottom surface, and the first axis is substantially parallel to the bottom surface.
18. The apparatus of claim 17 , further comprising an adhesive applied to the bottom surface of the base, wherein the adhesive is configured to attach to the apparatus to a skin surface of a subject.
19. The apparatus of claim 8 , wherein the housing includes a base, and the portion of the housing is connected to the base.
20. The apparatus of claim 8 , wherein the proximal projection of the first cog has an angled face.