IP Library › Granted Patent US 11,535,650
Granted Patent B1
US 11,535,650 · App. 17/724,304 · Granted Dec 27, 2022

Modulation of complement activity

Inventors: Michelle Denise Hoarty (Billerica, MA); Ketki Ashok Dhamnaskar (Foster City, CA); Daniel Elbaum (Newton, MA); Kristopher Josephson (San Carlos, CA); Kelley Cronin Larson (Quincy, MA); Zhong Ma (Lexington, MA); Nathan Ezekiel Nims (Winchester, MA); Alonso Ricardo (Winchester, MA); Kathleen Seyb (Wakefield, MA); Guo-Qing Tang (Acton, MA); Douglas A. Treco (Arlington, MA); Zhaolin Wang (Wellesley, MA); Ping Ye (Lexington, MA); Hong Zheng (New York, NY); Sarah Jacqueline Perlmutter (Urbana, IL); Robert Paul Hammer (Maynard, MA)
Assignee: RA PHARMACEUTICALS, INC.
C07K7/08A61K47/64A61K47/645C07K7/06C07K16/00A61K38/00
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Quick Facts
Patent No.
US 11,535,650
App. No.
17/724,304
Granted
Dec 27, 2022
Kind
B1
Abstract

The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Claims (5)

1. A pharmaceutical composition comprising:

a polypeptide of the formula:

(SEQ ID NO: 194); and

a pharmaceutically acceptable carrier or excipient.

2. The pharmaceutical composition of claim 1 , wherein the pharmaceutical composition is a sterile aqueous solution.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 20, 2025
From: RA PHARMACEUTICALS, INC.
To: UCB HOLDINGS, INC.
Reel/Frame 071466/0238 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 22, 2022
From: HOARTY, MICHELLE DENISE; DHAMNASKAR, KETKI ASHOK; ELBAUM, DANIEL; JOSEPHSON, KRISTOPHER; LARSON, KELLEY CRONIN; MA, ZHONG; NIMS, NATHAN EZEKIEL; RICARDO, ALONSO; SEYB, KATHLEEN; TANG, GUO-QING; TRECO, DOUGLAS A.; WANG, ZHAOLIN; YE, PING; ZHENG, HONG; PERLMUTTER, SARAH JACQUELINE; HAMMER, ROBERT PAUL
To: RA PHARMACEUTICALS, INC.
Reel/Frame 059686/0365 →
Continuity (9)
Continuation 17236247 · Apr 21, 2021
Continuation 16732502 · Jan 2, 2020
Continuation 16554665 · Aug 29, 2019
Continuation 16237893 · Jan 2, 2019
Continuation 16128561 · Sep 12, 2018
Continuation 15318063
Provisional Application 62108772 · Jan 28, 2015
Provisional Application 62077460 · Nov 10, 2014
Provisional Application 62011368 · Jun 12, 2014