IP Library › Granted Patent US 11,553,889
Granted Patent B2
US 11,553,889 · App. 16/748,928 · Granted Jan 17, 2023

Devices, systems, and methods for improved accuracy model of vessel anatomy

Inventors: Jason Spencer (San Diego, CA); Joseph Hoffman (Sacramento, CA)
Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
A61B6/5247A61B6/12A61B6/485A61B6/487A61B6/504A61B8/0841A61B8/12A61B8/4263A61B8/5261A61B90/39G01S15/899G01S15/8952A61B8/06A61B8/0891G01S7/52036G01S15/894G01S15/8922G01S15/8981
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Quick Facts
Patent No.
US 11,553,889
App. No.
16/748,928
Granted
Jan 17, 2023
Kind
B2
Abstract

Devices, systems, and methods of imaging a blood vessel are provided. For example, the method can include obtaining fluoroscopic image data of a region of interest in a blood vessel using an x-ray source; obtaining intravascular ultrasound (IVUS) data at a plurality of positions across the region of interest using an IVUS component disposed on an intravascular device; processing the fluoroscopic image data and IVUS data, including: determining, using the fluoroscopic image data, a position of the intravascular device with respect to the x-ray source at each of the plurality of positions across the region of interest; co-registering the fluoroscopic image data and the IVUS image data; and generating, a model of the region of interest including position information of a border of a lumen of the blood vessel at each of the plurality of locations; and outputting a visual representation of the model of the region of interest.

Claims (64)

1. A system, comprising:

an intravascular ultrasound (IVUS) imaging catheter configured to acquire IVUS image data of a blood vessel of a patient;

a processor in communication with the IVUS imaging catheter and configured to:

receive the IVUS image data from the IVUS imaging catheter, wherein the IVUS image data is associated with different frequencies of ultrasound emissions;

determine, using the IVUS image data, a plurality of structural characteristics of tissue forming a wall of the blood vessel, wherein determining the plurality of structural characteristics includes distinguishing different types of structural characteristics from one another using the different frequencies of ultrasound emissions;

generate a visual representation of the blood vessel based on determining the plurality of structural characteristics; and

output the visual representation to a monitor in communication with the processor,

wherein the IVUS imaging catheter is configured to separate different exposures of ultrasound emissions in time by transmitting:

at a first time, an ultrasound emission associated with a first frequency;

at a second time, an ultrasound emission associated with a second frequency with a first gain value; and

at a third time, an ultrasound emission associated with the second frequency with a second gain value.

2. The system of claim 1 , wherein the blood vessel is a peripheral blood vessel.

3. The system of claim 1 , wherein the processor is further configured to reduce speckle in the IVUS image data by combining information from the different exposures.

4. The system of claim 3 , wherein the visual representation is based on the IVUS image data with reduced speckle.

5. The system of claim 1 , wherein the visual representation comprises color indications of determined positions of at least one of a blood-tissue boundary, a media-adventitia boundary, or stent strut locations.

6. The system of claim 5 , wherein the visual representation comprises a cross-sectional representation of the blood vessel.

7. The system of claim 5 , wherein the visual representation comprises a longitudinal representation of the blood vessel.

8. The system of claim 7 , wherein the longitudinal representation of the blood vessel comprises an indication of a position of minimal lumen area in the blood vessel, wherein the position of the minimal lumen area is calculated based on the blood-tissue boundary.

9. The system of claim 8 , wherein the longitudinal representation of the blood vessel comprises an indication of a position of the blood vessel that is un-stenosed and closest to the position of the minimal lumen area.

10. The system of claim 5 , wherein the processor is further configured to verify a deployment of a stent within the blood vessel, including determining whether struts of the stent are apposed to the blood-tissue boundary of the blood vessel.

11. The system of claim 10 , wherein the visual representation further comprises an indication of positions of the struts of the stent within the blood vessel.

12. A system, comprising:

an intravascular ultrasound (IVUS) imaging catheter configured to acquire IVUS image data of a blood vessel of a patient

a processor in communication with the IVUS imaging catheter and configured to:

receive the IVUS image data from the IVUS imaging catheter, wherein the IVUS image data is associated with different frequencies of ultrasound emissions;

determine, using the IVUS image data, a plurality of structural characteristics of tissue forming a wall of the blood vessel, wherein determining the plurality of structural characteristics includes distinguishing different types of structural characteristics from one another using the different frequencies of ultrasound emissions;

generate a visual representation of the blood vessel based on determining the plurality of structural characteristics; and

output the visual representation to a monitor in communication with the processor,

wherein the visual representation comprises color indications of determined positions of at least one of a blood-tissue boundary, a media-adventitia boundary, or stent strut locations,

wherein the visual representation comprises a longitudinal representation of the blood vessel

wherein the longitudinal representation of the blood vessel comprises an indication of a position of minimal lumen area in the blood vessel,

wherein the position of the minimal lumen area is calculated based on the blood-tissue boundary.

13. The system of claim 12 , wherein the blood vessel is a peripheral blood vessel.

14. The system of claim 12 , wherein the IVUS imaging catheter is configured to separate different exposures of ultrasound emissions in time by transmitting:

at a first time, an ultrasound emission associated with a first frequency;

at a second time, an ultrasound emission associated with a second frequency with a first gain value; and

at a third time, an ultrasound emission associated with the second frequency with a second gain value.

15. The system of claim 14 , wherein the processor is further configured to reduce speckle in the IVUS image data by combining information from the different exposures.

16. The system of claim 15 , wherein the visual representation is based on the IVUS image data with reduced speckle.

17. The system of claim 12 , wherein the visual representation comprises a cross-sectional representation of the blood vessel.

18. The system of claim 12 , wherein the longitudinal representation of the blood vessel comprises an indication of a position of the blood vessel that is un-stenosed and closest to the position of the minimal lumen area.

19. The system of claim 12 , wherein the processor is further configured to verify a deployment of a stent within the blood vessel, including determining whether struts of the stent are apposed to the blood-tissue boundary of the blood vessel.

20. The system of claim 19 , wherein the visual representation further comprises an indication of positions of the struts of the stent within the blood vessel.

21. A system, comprising:

an intravascular ultrasound (IVUS) imaging catheter configured to acquire IVUS image data of a blood vessel of a patient

a processor in communication with the IVUS imaging catheter and configured to:

receive the IVUS image data from the IVUS imaging catheter, wherein the IVUS image data is associated with different frequencies of ultrasound emissions;

determine, using the IVUS image data, a plurality of structural characteristics of tissue forming a wall of the blood vessel, wherein determining the plurality of structural characteristics includes distinguishing different types of structural characteristics from one another using the different frequencies of ultrasound emissions;

generate a visual representation of the blood vessel based on determining the plurality of structural characteristics; and

output the visual representation to a monitor in communication with the processor,

wherein the visual representation comprises color indications of determined positions of at least one of a blood-tissue boundary, a media-adventitia boundary, or stent strut locations,

wherein the processor is further configured to verify a deployment of a stent within the blood vessel, including determining whether struts of the stent are apposed to the blood-tissue boundary of the blood vessel.

22. The system of claim 21 , wherein the blood vessel is a peripheral blood vessel.

23. The system of claim 21 , wherein the IVUS imaging catheter is configured to separate different exposures of ultrasound emissions in time by transmitting:

at a first time, an ultrasound emission associated with a first frequency;

at a second time, an ultrasound emission associated with a second frequency with a first gain value; and

at a third time, an ultrasound emission associated with the second frequency with a second gain value.

24. The system of claim 23 , wherein the processor is further configured to reduce speckle in the IVUS image data by combining information from the different exposures.

25. The system of claim 24 , wherein the visual representation is based on the IVUS image data with reduced speckle.

26. The system of claim 21 , wherein the visual representation comprises a cross-sectional representation of the blood vessel.

27. The system of claim 21 , wherein the visual representation comprises a longitudinal representation of the blood vessel.

28. The system of claim 27 , wherein the longitudinal representation of the blood vessel comprises an indication of a position of minimal lumen area in the blood vessel, wherein the position of the minimal lumen area is calculated based on the blood-tissue boundary.

29. The system of claim 28 , wherein the longitudinal representation of the blood vessel comprises an indication of a position of the blood vessel that is un-stenosed and closest to the position of the minimal lumen area.

30. The system of claim 21 , wherein the visual representation further comprises an indication of positions of the struts of the stent within the blood vessel.

Continuity (3)
Continuation 14798218 · Jul 13, 2015
Provisional Application 62024339 · Jul 14, 2014
Related Publication 20200155107A1 · May 21, 2020
Cited By (9)
US 12,318,636 US 12,343,568 US 12,390,665 US 12,446,905 US 12,527,976 US 12,582,848 US 12,599,787 US 12,642,993 US 12,642,994