IP Library Granted Patent US 11,560,392
Granted Patent B2
US 11,560,392 · App. 17/115,514 · Granted Jan 24, 2023

Boron-containing compounds

Inventors: Franz Amann (Hunzenschwil, CH); Matthew M. Bio (Cambridge, MA); Jonas Bürgler (Hunzenschwil, CH); Yuanqing Fang (Cambridge, MA); David Ford (Cambridge, MA); Daniel McGarry (Malvern, PA)
Assignee: VENATORX PHARMACEUTICALS, INC.
C07F5/025
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Quick Facts
Patent No.
US 11,560,392
App. No.
17/115,514
Granted
Jan 24, 2023
Kind
B2
Abstract

Described herein are boron-containing compounds, compositions, and methods for their preparation.

Claims (11)

1. A compound of Formula (A), or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof:

wherein

n is 1 or 2;

p is 1;

CycA is an optionally substituted cyclohexane;

each Y is independently —NR 4 R 5 or —NR 4 (CR 6 R 7 ) v NR 4 R 5 ;

each R 1 and R 2 are hydrogen;

R 4 and R 5 are hydrogen;

each R 6 and R 7 are hydrogen; and

v is 2 or 3;

wherein the compound of Formula (A) is free of trifluoroacetic acid and is more than about 97% pure (mole %).

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2021
From: MCGARRY, DANIEL
To: VENATORX PHARMACEUTICALS, INC.
Reel/Frame 055199/0400 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2021
From: AMANN, FRANZ; BÜRGLER, JONAS
To: CARBOGEN AMCIS AG
Reel/Frame 055200/0790 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2021
From: CARBOGEN AMCIS AG
To: VENATORX PHARMACEUTICALS, INC.
Reel/Frame 055201/0291 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2021
From: SNAPDRAGON CHEMISTRY, INC.
To: VENATORX PHARMACEUTICALS, INC.
Reel/Frame 055201/0403 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2021
From: BIO, MATTHEW; FANG, YUANQING; FORD, DAVID
To: SNAPDRAGON CHEMISTRY, INC.
Reel/Frame 055265/0469 →
Continuity (3)
Division 16322372
Provisional Application 62370917 · Aug 4, 2016
Related Publication 20210163506A1 · Jun 3, 2021
Cited By (2)
US 12,187,752 US 12,606,573