Compounds for the prevention and treatment of diseases and the use thereof
Aspects of the invention relate to novel synthetic compounds having binding affinity with galectin proteins.
1. A compound or a pharmaceutically acceptable salt or solvate thereof having the structure
Structure
2. The compound of claim 1 , wherein the compound has an affinity of about 1 nM to about 50 μM for Galectin-3.
3. A composition comprising a therapeutically effective amount of the compound of claim 1 and a pharmaceutically acceptable adjuvant, excipient, formulation carrier or combinations thereof.
4. A composition comprising a therapeutically effective amount of the compound claim 1 and a therapeutically effective amount of an anti-inflammatory drug, vitamin, pharmaceutical drug, nutraceutical drug, supplement, or combinations thereof.