Provided is a bioimplant which is capable to inhibit the biofilm formation over a long period of time after an operation. The bioimplant of the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal-spray film is 0.05 wt % to 3.00 wt %.
1. A bioimplant, comprising
a base material of the bioimplant;
a coating film comprising a calcium phosphate-based material and a silver material formed on at least a part of a surface of the base material;
wherein the calcium phosphate-based material comprises oxyapatite and hydroxyapatite, wherein the hydroxyapatite is formed from converting oxyapatite present in the coating into the hydroxyapatite by immersing the coating in deionized water, and
wherein fine crystals of the hydroxyapatite are present on a surface of the coating film, wherein a size of the fine crystals of hydroxyapatite is in a range of 0.01 μm to 2.00 μm in length, thickness or width.
2. The bioimplant according to claim 1 , wherein the silver material concentration in the coating film is in a range of 0.05 wt % to 3.00 wt %.
3. The bioimplant according to claim 1 , wherein the base material comprises a metal.
4. The bioimplant according to claim 1 , wherein the calcium phosphate-based material further comprises a compound or a mixture of two or more compounds selected from the group consisting of alpha-tricalcium phosphate, beta-tricalcium phosphate, and tetracalcium phosphate.
5. The bioimplant according to claim 1 , wherein the bioimplant has a bone contact portion, at least part of the bone contact portion is covered with the coating film.