Pharmaceutical compositions for combination therapy
The present invention relates to a combination of active ingredients for use in the treatment of diseases.
1. A method for treating a cholestatic disease, wherein said method comprises administering to a subject in need thereof a therapeutically effective amount of a combination of:
(i) cenicriviroc or a pharmaceutically acceptable salt thereof; and
(ii) elafibranor or a pharmaceutically acceptable salt thereof.
2. The method according to claim 1 , wherein the disease is selected in the group consisting of Primary Sclerosing Cholangitis (PSC), Primary Biliary Cholangitis (PBC), biliary atresia, and familial intrahepatic cholestasis type 3 (PFIC3).
3. The method according to claim 1 , comprising administering a pharmaceutical composition comprising components (i) and (ii) and a pharmaceutically acceptable carrier.
4. The method according to claim 1 , wherein components (i) and (ii) are administered sequentially.
5. The method according to claim 1 , wherein components (i) and (ii) are administered separately.
6. The method according to claim 1 , wherein components (i) and (ii) are administered simultaneously.
7. The method according to claim 1 , wherein the cholestatic disease is PBC.
8. The method according to claim 1 , wherein the cholestatic disease is PSC.