IP Library › Granted Patent US 11,612,565
Granted Patent B2
US 11,612,565 · App. 16/760,363 · Granted Mar 28, 2023

Aerosolizable gel

Inventors: John Yao (Cambridge, MA); Joseph McLellan (Cambridge, MA); Xinhua Li (Cambridge, MA); Hootan Farhat (Cambridge, MA); Michael Bates (Cambridge, MA)
Assignee: Nicoventures Trading Limited
A61K9/007A24B15/167A24F40/20A24F40/10
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Quick Facts
Patent No.
US 11,612,565
App. No.
16/760,363
Granted
Mar 28, 2023
Kind
B2
Abstract

There is provided an aerosolizable gel comprising (a) an active agent; (b) one or more gel forming materials, wherein the one or more gel forming material is at least one phyllosilicate; (c) an aerosol forming material selected from glycerol, propylene glycol and mixtures thereof; and (d) water.

Claims (41)

1. A dosage form of an aerosolizable product, wherein the dosage form of the aerosolizable gel comprises:

(a) nicotine in an amount of 0.5 to 10 mg;

(b) one or more gel forming materials, wherein the one or more gel forming materials is at least kaolinite;

(c) an aerosol forming material; and

(d) water.

2. An aerosolizable gel according to claim 1 wherein the nicotine is present in an amount of no greater than 2 wt % based on the total weight of the aerosolizable gel.

3. An aerosolizable gel according to claim 1 wherein the nicotine is present in an amount of no greater than 1.8 wt % based on the total weight of the aerosolizable gel.

4. An aerosolizable gel according to claim 1 wherein the kaolinite is present in an amount of 10 to 80 wt. % based on the aerosolizable gel.

5. An aerosolizable gel according to claim 1 wherein the kaolinite is present in an amount of 20 to 70 wt. % based on the aerosolizable gel.

6. An aerosolizable gel according to claim 1 wherein the kaolinite is present in an amount of 30 to 60 wt. % based on the aerosolizable gel.

7. An aerosolizable gel according to claim 1 wherein the aerosol forming material is selected from glycerol, propylene glycol and mixtures thereof.

8. An aerosolizable gel according to claim 1 wherein the aerosol forming material is a combination of glycerol and propylene glycol.

9. An aerosolizable gel according to claim 1 wherein the aerosol forming material is present in an amount of 10 to 60 wt. % based on the aerosolizable gel.

10. An aerosolizable gel according to claim 1 wherein the aerosol forming material is present in an amount of 20 to 40 wt. % based on the aerosolizable gel.

11. An aerosolizable gel according to claim 1 wherein the water is present in an amount of 1 to 40 wt. % based on the aerosolizable gel.

12. An aerosolizable gel according to claim 1 wherein the water is present in an amount of 1 to 20 wt. % based on the aerosolizable gel.

13. A method of forming an aerosol, the method comprising the step of heating an aerosolizable gel comprising;

(a) an active agent;

(b) a gel forming material, wherein the gel forming material is at least kaolinite;

(c) an aerosol forming material; and

(d) water.

14. A method of forming an aerosol according to claim 13 wherein the aerosol forming material is selected from glycerol, propylene glycol and mixtures thereof.

15. A method of forming an aerosol according to claim 13 wherein the aerosolizable gel is an aerosolizable gel comprises:

nicotine in an amount of no greater than 2 wt % based on the total weight of the aerosolizable gel;

kaolinite in an amount of 10 to 80 wt. % based on the aerosolizable gel;

the aerosol forming material is present in an amount of 10 to 60 wt. % based on the aerosolizable gel; and

water present in an amount of 1 to 20 wt. % based on the aerosolizable gel.

16. An electronic vapour provision system comprising:

(i) an aerosolizable gel comprising

(a) an active agent;

(b) one or more gel forming materials, wherein the one or more gel forming material is at least kaolinite;

(c) an aerosol forming material; and

(d) water;

(ii) a heater for heating the aerosolizable gel and thereby vaporising some or all of the aerosolizable gel for inhalation by a user of the electronic vapour provision system.

17. A method of forming an aerosol according to claim 16 wherein the aerosolizable gel is an aerosolizable gel comprising:

nicotine in an amount of no greater than 2 wt % based on the total weight of the aerosolizable gel;

kaolinite in an amount of 10 to 80 wt. % based on the aerosolizable gel;

the aerosol forming material is present in an amount of 10 to 60 wt. % based on the aerosolizable gel; and

water present in an amount of 1 to 20 wt. % based on the aerosolizable gel.

18. The method of claim 13 , wherein the aerosol forming material is a combination of glycerol and propylene glycol.

19. The method of claim 16 , wherein the aerosol forming material is a combination of glycerol and propylene glycol.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2022
From: YAO, JOHN; MCLELLAN, JOSEPH; LI, XINHUA; FARHAT, HOOTAN; BATES, MICHAEL
To: NICOVENTURES TRADING LIMITED
Reel/Frame 061599/0651 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2022
From: BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED
To: NICOVENTURES TRADING LIMITED
Reel/Frame 061814/0522 →
Priority Claims (1)
GB 1718032 · Nov 1, 2017 · national
Continuity (1)
Related Publication 20210177039A1 · Jun 17, 2021