IP Library › Granted Patent US 11,622,998
Granted Patent B2
US 11,622,998 · App. 17/112,935 · Granted Apr 11, 2023

Anti-inflammatory peptides and composition comprising the same

Inventors: Sang Jae Kim (Seoul, KR); Kyung Hee Kim (Seongnam-si, KR); Kyu-Yong Lee (Seongnam-si, KR); Seong-Ho Koh (Seongnam-si, KR); Hyun-Hee Park (Seongnam-si, KR); Sung Jin Huh (Seongnam-si, KR); Woo Jin Lee (Seongnam-si, KR); Bum Joon Kim (Seongnam-si, KR)
Assignee: GemVax & KAEL Co., Ltd.
A61K38/45A23L33/18A61K8/64A61Q19/00C07K7/08C07K14/4703C12N9/0069C12N9/0083C12Y113/11C12Y114/99001C12Y207/07049A23V2002/00A61K38/00Y02A50/30
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Quick Facts
Patent No.
US 11,622,998
App. No.
17/112,935
Granted
Apr 11, 2023
Kind
B2
Abstract

A peptide with anti-inflammatory activity is described, wherein the peptide comprises at least one amino acid sequence among SEQ ID NO: 2 to SEQ ID NO: 179, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. An inflammatory composition comprising the above mentioned peptides is also described. The peptides that have at least one amino acid sequence of SEQ ID NO: 2 to SEQ ID NO: 179 shows outstanding efficacy in both suppressing inflammation and in prophylactic means, Therefore, the composition comprising those peptides can be used as anti-inflammatory pharmaceutical compositions or as cosmetic compositions, in turn, treating and preventing a variety of different types of inflammatory diseases.

Claims (7)

1. A composition comprising a peptide having anti-inflammatory activity, wherein the peptide consists of the amino acid sequence of SEQ ID NO: 108.

2. The composition according to claim 1 , which the peptide originates from human telomerase.

3. An anti-inflammatory composition comprising the peptide according to claim 1 as an active ingredient.

4. The anti-inflammatory composition according to claim 3 for treatment of inflammatory diseases, wherein the inflammatory disease is a central or peripheral nervous system related disease.

5. The anti-inflammatory composition according to claim 3 , which is a pharmaceutical composition for treatment of inflammatory diseases, wherein the inflammatory disease is a central or peripheral nervous system related disease.

6. The anti-inflammatory composition according to claim 5 , wherein the central or peripheral nervous system related diseases is selected from the group consisting of Alzheimer's disease, meningitis, encephalitis, multiple sclerosis, cerebral infarction, cerebral embolism, Guillain-Barre syndrome, neuritis, and uveitis.

7. A method for treating inflammatory diseases by administering the composition according to claim 1 , wherein the inflammatory disease is a central or peripheral nervous system related disease selected from the group consisting of Alzheimer's disease, meningitis, encephalitis, multiple sclerosis, cerebral infarction, cerebral embolism, Guillain-Barre syndrome, neuritis and uveitis.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2021
From: KIM, SANG JAE
To: GEMVAX & KAEL CO., LTD.
Reel/Frame 055929/0088 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2021
From: KIM, KYUNG HEE; LEE, KYU-YONG; KOH, SEONG-HO; PARK, HYUN-HEE; HUH, SUNG JIN; LEE, WOO JIN; KIM, BUM JOON
To: GEMVAX & KAEL CO., LTD.
Reel/Frame 055930/0763 →
Priority Claims (5)
KR 10-2012-0050529 · May 11, 2012 · national
KR 10-2012-0050533 · May 11, 2012 · national
KR 10-2012-0071989 · Jul 2, 2012 · national
KR 10-2012-0104144 · Sep 19, 2012 · national
KR 10-2012-0104207 · Sep 19, 2012 · national
Continuity (4)
Division 16230732 · Dec 21, 2018
Division 15354139 · Nov 17, 2016
Division 14400321
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