IP Library Granted Patent US 11,624,074
Granted Patent B2
US 11,624,074 · App. 14/443,357 · Granted Apr 11, 2023

Mutations in solanaceae plants that modulate shoot architecture and enhance yield-related phenotypes

Inventors: Zachary Lippman (North Bellmore, NY); Soon-Ju Park (Cold Spring Harbor, NY)
Assignee: Cold Spring Harbor Laboratory
C12N15/827A01H1/02A01H5/08A01H6/825C07K14/415C12N15/8261
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,624,074
App. No.
14/443,357
Granted
Apr 11, 2023
Kind
B2
Abstract

Provided herein are genetically-altered Solanaceae plants, compositions related to the Solanaceae plants, and methods of making the Solanaceae plants.

Claims (23)

1. A genetically-altered tomato plant homozygous for a mutant self-pruning (sp) gene and heterozygous for a mutant single flower truss (sft) gene, wherein the mutant sft gene encodes a mutant sft polypeptide comprising the amino acid sequence of SEQ ID NO: 21.

2. A genetically-altered tomato plant homozygous for a mutant self-pruning (sp) gene that encodes a mutant sp polypeptide comprising the amino acid sequence of SEQ ID NO: 10 and heterozygous for a mutant single flower truss (sft) gene comprising a coding sequence having the nucleic acid sequence of SEQ ID NO: 20.

3. A genetically-altered tomato plant homozygous for a mutant self-pruning (sp) gene and heterozygous for a mutant single flower truss (sft) gene, wherein the mutant sp gene comprises a coding sequence having the nucleic acid sequence of SEQ ID NO: 8 or a coding sequence at least 99% identical to SEQ ID NO: 8 and the mutant sft gene is sft-1906.

4. A genetically-altered tomato plant homozygous for a mutant self-pruning (sp) gene and heterozygous for a mutant single flower truss (sft) gene, wherein the mutant sft gene comprises a coding sequence having a mutation at position 394 of the nucleic acid sequence of SEQ ID NO: 18.

5. A genetically-altered tomato plant homozygous for a mutant self-pruning (sp) gene and heterozygous for a mutant single flower truss (sft) gene, wherein the mutant sft gene encodes a mutant sft polypeptide comprising an amino acid sequence having a mutation at position 132 of the amino acid sequence of SEQ ID NO: 19.

6. The genetically-altered tomato plant of claim 5 , wherein the genetically-altered tomato plant is isogenic.

7. The genetically-altered tomato plant of claim 5 , wherein the genetically-altered tomato plant is inbred.

8. A seed for producing the genetically-altered tomato plant of claim 5 .

9. The genetically-altered tomato plant of claim 5 , wherein the genetically-altered tomato plant has a sympodial index of between 1 and 3.

10. The genetically-altered tomato plant of claim 5 , wherein the genetically-altered tomato plant has a sympodial index of between 1.5 and 2.5.

11. The genetically-altered tomato plant of claim 5 , wherein the genetically-altered tomato plant has a sympodial index of less than 3.

12. The genetically-altered tomato plant of claim 5 , wherein the genetically-altered tomato plant has a sympodial index of less than 2.5.

13. The genetically-altered tomato plant of claim 5 , wherein the genetically-altered tomato plant has a sympodial index of less than 2.

14. The genetically-altered tomato plant of claim 5 , wherein the genetically-altered tomato plant has a sympodial index of less than 1.

15. The genetically-altered tomato plant of claim 5 , wherein the mutant sft gene encodes a mutant sft polypeptide that comprises a Val to Met mutation.

16. A genetically-altered tomato plant homozygous for a mutant self-pruning (sp) gene that comprises a coding sequence having the nucleic acid sequence of SEQ ID NO: 8 or a coding sequence having a nucleic acid sequence having at least 99% identity with the sequence of SEQ ID NO: 8 and heterozygous for a mutant single flower truss (sft) gene,

wherein the mutant sft gene comprises a coding sequence having a nucleic acid sequence having at least 99% identity with the sequence of SEQ ID NO: 18 and a mutation at any position from position 379 through position 420 of the nucleic acid sequence of SEQ ID NO: 18,

wherein the mutant sft gene coding sequence has a nucleic acid sequence having at least 95% identity with the sequence of SEQ ID NO: 18 from position 379 through position 420, and

wherein the genetically-altered tomato plant exhibits: modified flowering time and shoot architecture, higher yield, higher brix, higher brix yield, higher red fruit yield, or any combination thereof, compared to a corresponding genetically-altered tomato plant homozygous for a mutant sp gene.

17. A genetically-altered tomato plant homozygous for a mutant self-pruning (sp) gene that comprises a coding sequence having the nucleic acid sequence of SEQ ID NO: 8 or a coding sequence having a nucleic acid sequence having at least 99% identity with the sequence of SEQ ID NO: 8 and heterozygous for a mutant single flower truss (sft) gene,

wherein the mutant sft gene comprises a coding sequence having a nucleic acid sequence having at least 99% identity with the sequence of SEQ ID NO: 18 and a mutation at any position from position 379 through position 420 of the nucleic acid sequence of SEQ ID NO: 18,

wherein the mutant sft gene coding sequence has a nucleic acid sequence having at least 97% identity with the sequence of SEQ ID NO: 18 from position 379 through position 420, and

wherein the genetically-altered tomato plant exhibits: modified flowering time and shoot architecture, higher yield, higher brix, higher brix yield, higher red fruit yield, or any combination thereof, compared to a corresponding genetically-altered tomato plant homozygous for a mutant sp gene.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 4, 2017
From: LIPPMAN, ZACHARY
To: COLD SPRING HARBOR LABORATORY
Reel/Frame 042240/0538 →
CONFIRMATORY LICENSE Recorded Apr 27, 2017
From: COLD SPRING HARBOR LABORATORY
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 042348/0180 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 6, 2017
From: PARK, SOON-JU
To: COLD SPRING HARBOR LABORATORY
Reel/Frame 041886/0362 →
Continuity (4)
Continuation In Part 13799831 · Mar 13, 2013
Provisional Application 61869052 · Aug 22, 2013
Provisional Application 61728654 · Nov 20, 2012
Related Publication 20150284732A1 · Oct 8, 2015
Cited By (2)
US 12,270,035 US 12,668,807