Implantable component with socket
Implantable devices may include a single, first component or a plurality of components such as first and second components, the second component being flexibly coupled to the first component. A socket extends over one or more of the component(s), the socket being configured to enhance the inter-component interaction and/or including one or more exposed surface(s) configured to exhibit one or more tiers of foreign body responses within a range of possible foreign body responses.
1. An implantable device comprising:
a first component having a first outer profile defining first radial variability along the first component; and
a socket extending over the first outer profile of the first component to define a second outer profile having a second radial variability that is reduced relative to the first radial variability, wherein the socket includes one or more outer exposed surfaces having one or more material porosities, wherein the socket is formed of one or more layers of material including a fibril microstructure in which an orientation of the fibril microstructure is in a direction aligned to a longitudinal axis of socket.
2. The implantable device of claim 1 , wherein the one or more outer exposed surfaces having the one or more material porosities configured to exhibit extracellular matrix integration.
3. The implantable device of claim 1 , wherein the socket includes one or more layers of material that is impermeable to cellular integration.
4. The implantable device of claim 1 , wherein the socket includes one or more reinforcing rings.
5. The implantable device of claim 4 , wherein at least one of the one or more reinforcing rings is elastically deformable to an enlarged diameter from which the one or more reinforcing rings elastically recovers.
6. The implantable device of claim 5 , wherein the one or more reinforcing rings defines a continuous, helical undulating pattern.
7. The implantable device of claim 1 , wherein the socket includes an outwardly flared end.
8. The implantable device of claim 1 , wherein the socket includes a reinforced end.
9. The implantable device of claim 1 , wherein at least one of an outer and an inner surface of the socket includes material configured to promote tissue ingrowth.
10. The implantable device of claim 1 , wherein the socket is formed from a material set including ePTFE graft material, elastomer material, other polymeric material, or a combination of two or more such materials.
11. The implantable device of claim 1 , wherein the socket includes an ePTFE stretch graft material.
12. The implantable device of claim 1 , wherein the socket includes material that is partially or fully bio-resorbable and/or partially or fully bio-absorbable.
13. The implantable device of claim 1 , wherein the socket includes materials that are partially or fully bio-resorbable or bio-absorbable and is configured to provide temporary fixation to body tissue that degrades partially or fully over time.
14. The implantable device of claim 1 , wherein the socket includes one or more layers configured as a mesh or network of material that is adapted to enhance biocompatibility and fibrosis following implantation.
15. The implantable device of claim 14 , wherein the mesh or network of material is formed by crossing strands of material or by intermittent voids or openings in one or more layers of material.
16. The implantable device of claim 1 , configured as a transcatheter mitral chordal repair device or a blood pump device.
17. An implantable device comprising:
a first component;
a second component flexibly coupled to the first component;
a socket extending over the first component and the second component, the socket being configured to enhance an inter-component interaction between the first and second components of the implantable device by holding the second component in position and reducing relative movement between the first and second components, wherein the socket includes one or more outer exposed surfaces having one or more material porosities, the one or more outer exposed surfaces configured to exhibit one or more tiers of foreign body responses within a range of possible foreign body responses; and
a third component and fourth component, the socket being configured to receive the third and fourth components to enhance an inter-component interaction between the first and third components of the implantable device, wherein the third component is a tether lock component and the fourth component is a tether component.
18. The implantable device of claim 17 , wherein the first component is an anchor component and the second component is a tether component.
19. A method comprising:
delivering a multi-component device to a location in a body of a patient, the multi-component device including a first component having a first outer profile defining first radial variability along the first component; and a socket extending over the first outer profile of the first component to define a second outer profile having a second radial variability that is reduced relative to the first radial variability, wherein the socket includes one or more outer exposed surfaces having one or more material porosities, wherein the socket is formed of one or more layers of material including a fibril microstructure in which an orientation of the fibril microstructure is in a direction aligned to a longitudinal axis of socket; and
inserting a third component into the socket to enhance the inter-component interaction between the first and third components of the implantable device.
20. The method of claim 19 , wherein the third component is a tether lock component.