Electrical stimulation with thermal treatment or thermal monitoring
Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit configured to generate one or more electric fields and a control circuit in communication with the electric field generating circuit. The control circuit configured to control delivery of the one or more electric fields from the electric field generating circuit. The system can include two or more electrodes to deliver the electric fields to a site of a cancerous tumor within a patient and a temperature sensor to measure the temperature of tissue at the site of the cancerous tumor. The control circuit can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz. Other embodiments are also included herein.
1. A medical device system comprising:
an electric field generating circuit configured to generate one or more electric fields; and
a control circuit in communication with the electric field generating circuit, the control circuit configured to control delivery of the one or more electric fields from the electric field generating circuit;
two or more electrodes forming at least one electrode pair to deliver the one or more electric fields to a site of a cancerous tumor within a patient; and
wherein the control circuit causes the electric field generating circuit to generate the one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz, wherein the one or more electric fields are effective to disrupt cellular mitosis in a cancerous cell;
wherein the control circuit calculates a power output of the one or more electric fields and estimates a temperature of tissue within the one or more electric fields based on the power output and a distance between the two or more electrodes of the at least one electrode pair;
wherein the temperature of the tissue is estimated by dividing an average power output by the product of the distance between the two or more electrodes and a specific heat capacity of the tissue.
2. The medical device system of claim 1 , wherein the medical device system is configured to receive data regarding the distance between the two or more electrodes of the at least one electrode pair.
3. The medical device system of claim 1 , wherein the medical device system is configured to estimate the distance between the two or more electrodes of the at least one electrode pair based on impedance data.
4. The medical device system of claim 2 , wherein the medical device system receives the data regarding the distance between the two more electrodes from a user.
5. The medical device system of claim 4 , wherein the user determines the distance between the two or more electrodes using equipment selected from the group consisting of an imaging device, a fluoroscope, and an ultrasound imaging device.