IP Library › Granted Patent US 11,716,989
Granted Patent B2
US 11,716,989 · App. 16/945,279 · Granted Aug 8, 2023

Cadaver preservation systems and methods

Inventor: Joss Dean Fernandez (Columbia, MO)
Assignee: MAXIMUM FIDELITY SURGICAL SIMULATIONS, LLC
A01N1/00
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Quick Facts
Patent No.
US 11,716,989
App. No.
16/945,279
Granted
Aug 8, 2023
Kind
B2
Abstract

A system and method of preserving cadaveric tissue is provided. The present invention utilizes a preservation fluid having high-dose DMSO, high-dose acetic acid, and isopropyl alcohol. It is believed that the high-dose DMSO serves as a hardening agent while the high-dose acetic acid serves as a softening agent.

Claims (23)

1. A fluid for preserving cadaveric tissue, the fluid comprising:

an aprotic solvent in a first amount;

a weak acid in a second amount; and

a non-aldehyde oxygen-containing hydrocarbon in a third amount,

wherein the first amount is about 30% by volume of the fluid, wherein the second amount is about 60% by volume of the fluid, and wherein the third amount is about 10% by volume of the fluid.

2. The fluid of claim 1 , wherein the aprotic solvent is Dimethyl Sulfoxide (DMSO), wherein the weak acid is acetic acid, and wherein the non-aldehyde oxygen-containing hydrocarbon is isopropyl alcohol.

3. The fluid of claim 1 , wherein the aprotic solvent is Dimethyl Sulfoxide (DMSO).

4. The fluid of claim 1 , wherein, excluding any water associated with the weak acid, the fluid is an anhydrous solution.

5. The fluid of claim 4 , wherein the fluid is free of aldehyde.

6. The fluid of claim 1 , wherein the fluid consists of the aprotic solvent, the weak acid, and the non-aldehyde oxygen-containing hydrocarbon.

7. The fluid of claim 6 , wherein the pH of the weak acid is below 4.

8. The fluid of claim 7 , wherein the weak acid is glacial acetic acid.

9. A fluid for preserving cadaveric tissue, the fluid comprising:

an aprotic solvent in a first amount;

a weak acid in a second amount; and

a 140 proof alcohol in a third amount,

wherein the first amount is between about 15% and about 30% by volume of the fluid.

10. The fluid of claim 9 , wherein the aprotic solvent is Dimethyl Sulfoxide (DMSO), wherein the weak acid is acetic acid, and wherein the alcohol is isopropyl alcohol.

11. The fluid of claim 9 , wherein the aprotic solvent is Dimethyl Sulfoxide (DMSO).

12. The fluid of claim 9 , wherein the fluid is free of aldehyde.

13. The fluid of claim 12 , wherein the pH of the weak acid is below 4.

14. The fluid of claim 13 , wherein the weak acid is glacial acetic acid.

15. A method of preserving cadaveric tissue, the method comprising injecting into the cadaveric tissue the fluid according to claim 1 or 9 .

Assignments (2)
CHANGE OF NAME Recorded Feb 13, 2025
From: MAXIMUM FIDELITY SURGICAL SIMULATIONS, LLC
To: MAXIMUM FIDELITY SURGICAL SIMULATIONS, INC.
Reel/Frame 070969/0221 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 20, 2020
From: FERNANDEZ, JOSS DEAN
To: MAXIMUM FIDELITY SURGICAL SIMULATIONS, LLC
Reel/Frame 054431/0015 →
Continuity (2)
Provisional Application 62834668 · Apr 16, 2019
Related Publication 20210037809A1 · Feb 11, 2021