Blood treatment systems
Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.
1. A dialysis treatment apparatus comprising:
an elongate housing defining a longitudinal axis and including first and second end caps at opposite ends of the housing; and
a plurality of hollow membranous fibers within an interior of the housing between the first and second end caps, each hollow membranous fiber defining a lumen; and
a pump rotor in the first end cap,
wherein the dialysis treatment apparatus defines a blood flow path that extends through the first end cap, then through the lumens of the hollow membranous fibers, and then through the second end cap, and
wherein the blood flow path: (i) enters the first end cap transverse to the longitudinal axis, (ii) then transitions parallel to the longitudinal axis, (iii) then enters the pump rotor, and (iv) then, after exiting the pump rotor, extends toward the hollow membranous fibers.
2. The dialysis treatment apparatus of claim 1 , wherein the blood flow path enters the pump rotor along a center of the pump rotor.
3. The dialysis treatment apparatus of claim 2 , wherein the center of the pump rotor is on the longitudinal axis of the housing.
4. The dialysis treatment apparatus of claim 1 , wherein the blood flow path enters the first end cap between the pump rotor and the plurality of hollow membranous fibers.
5. The dialysis treatment apparatus of claim 1 , wherein the pump rotor comprises a centrifugal impeller such that the blood flow path exits the centrifugal impeller transverse to the longitudinal axis.
6. The dialysis treatment apparatus of claim 5 , wherein the first end cap redirects blood exiting the centrifugal impeller transverse to the longitudinal axis to flow parallel to the longitudinal axis toward the hollow membranous fibers.
7. The dialysis treatment apparatus of claim 1 , wherein the first end cap defines a toroidal space around the pump rotor.
8. The dialysis treatment apparatus of claim 1 , further comprising a check valve along the blood flow path.
9. The dialysis treatment apparatus of claim 1 , wherein the second end cap includes a port along the blood flow path for administering medicaments or extracting a fluid sample.
10. The dialysis treatment apparatus of claim 1 , wherein the housing further comprises a deaeration chamber along the blood flow path.
11. The dialysis treatment apparatus of claim 10 , wherein the deaeration chamber is defined in the second end cap.
12. The dialysis treatment apparatus of claim 1 , wherein the first end cap includes an internal support plate that defines one or more openings through which the blood flow path passes after the pump rotor and before the hollow membranous fibers.
13. The dialysis treatment apparatus of claim 1 , wherein the dialysis treatment apparatus is a dialyzer.