IP Library › Granted Patent US 11,771,124
Granted Patent B2
US 11,771,124 · App. 16/622,641 · Granted Oct 3, 2023

Composition comprising mannose oligosaccharide and process for making same and use thereof

Inventors: Bruno Frédéric Stengel (Auderghem, BE); Christof Franz Küsters (Krefeld, DE)
Assignee: Cargill, Incorporated
A23L33/125A23K20/163A23K50/30A23K50/60A23K50/75A23L33/40A61K8/60A61K31/702A61Q1/00A61Q11/00A61Q19/00A23V2002/00A61K2800/10
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Quick Facts
Patent No.
US 11,771,124
App. No.
16/622,641
Granted
Oct 3, 2023
Kind
B2
Abstract

The present invention relates to a composition comprising mannose oligosaccharide and a process for making such. The present invention further relates to a composition comprising mannose oligosaccharide for use in the treatment of a human or animal.

Claims (21)

1. A mannose oligosaccharide composition comprising:

a mannose oligosaccharide content of mannose oligosaccharide having a degree of polymerization (DP) of 3 or more that is 30 wt % db or higher; and

a dimannose content of from 10 to 35 wt % db;

wherein the composition has a water solubility of from 20 to 90% measured as a 10 wt % aqueous solution of the composition at 40° C.

2. The composition of claim 1 characterized in that it comprises less than 0.1 wt % db of beta-glucan.

3. The composition of claim 1 characterized in that it has a mannose oligosaccharide content of mannose oligosaccharide having a degree of polymerization (DP) of 3 or more that is 60 wt % db or higher.

4. The composition of claim 1 characterized in that it has a dimannose content of from 10 to 25 wt % db.

5. The composition of claim 1 characterized in that it has a fructose content of 0.5 to 10 wt % db.

6. A food, animal feed or pet food product comprising the composition of claim 1 and further food, animal feed or pet food ingredients.

7. The food, animal feed or pet food product of claim 6 wherein the composition of claim 1 is present in an amount of from 0.1 to 0.5 wt % based on the weight of the food, animal feed or pet food product.

8. The food, animal feed or pet food product of claim 6 wherein the composition of claim 1 is present in an amount of from 0.01 to 0.05 wt % based on the weight of the food, animal feed or pet food product.

9. The composition of claim 1 for treating human or animal.

10. The composition of claim 1 for reducing or preventing bacterial attachment to the intestinal mucosa and/or for improving weight gain and/or improving feed intake and/or improving body weight gain and/or improving stool quality in human or animal.

11. The composition of claim 1 characterized in that it has a mannose content of 5 to 25 wt % db.

12. The composition of claim 1 characterized in that it has a glucose content of 1 to 15 wt % db.

13. A cosmetic, personal care or pharmaceutical product comprising the mannose oligosaccharide composition according to claim 1 , wherein the cosmetic product is a makeup cream, makeup lotion or lipstick; the personal care product is an oral care product, hair care product, skin care product or hygiene product; or the pharmaceutical product is a disinfectant or an antiseptic balm.

14. A mannose oligosaccharide composition that has a water solubility of from 20 to 90% measured as a 10 wt % aqueous solution of the composition at 40° C. and that comprises less than 0.1 wt % db of beta-glucan, has a mannose oligosaccharide content of mannose oligosaccharide having a degree of polymerization (DP) of 3 or more that is 30 wt % db or higher, and has a dimannose content of from 10 to 35 wt % db.

15. The composition of claim 14 characterized in that it has having a fructose content of 0.5 to 10 wt % db, a mannose content of 5 to 25 wt % db, and/or a glucose content of 1 to 15 wt % db.

16. A process for making the mannose oligosaccharide composition of claim 1 , comprising:

a) polycondensing mannose by passing the mannose through a microreactor at a temperature of from 180° C. to 240° C. in the presence of an acidifying catalyst to produce manno-oligosaccharide composition, b) optionally neutralising and/or decolorizing the manno-oligosaccharide composition, and c) collecting the manno-oligosaccharide composition.

17. The process according to claim 16 wherein the residence time of mannose in the microreactor during step a) is from 5 to 20 seconds.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 26, 2022
From: STENGEL, BRUNO FREDERIC; KUSTERS, CHRISTOF FRANZ
To: CARGILL, INCORPORATED
Reel/Frame 060622/0199 →
Priority Claims (1)
EP 17175981 · Jun 14, 2017 · regional
Continuity (1)
Related Publication 20200297019A1 · Sep 24, 2020