IP Library Granted Patent US 11,771,665
Granted Patent B2
US 11,771,665 · App. 17/824,235 · Granted Oct 3, 2023

Compositions, methods of treatment, and containers including compositions

Inventors: Anuj Chauhan (Gainesville, FL); Phillip J. Dixon (Gainesville, FL)
Assignee: University of Florida Research Foundation, Inc.
A61K31/145A45C11/005A61F9/0008A61K9/0048A61K47/22A61K47/42
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Quick Facts
Patent No.
US 11,771,665
App. No.
17/824,235
Granted
Oct 3, 2023
Kind
B2
Abstract

Compositions for treatment of cystinosis, products for administering eye drops, and products for storing contact lenses are provided. Compositions include solutions that can contain an effective amount of cysteamine to treat cystinosis, and an oil with a lower density than the solution. Also provided is a product including a bottle for containing a solution, the bottle being substantially free of O 2 . Also provided is a contact lens holder for storing one or more contact lenses in a solution, the holder including barrier layers reducing the amount of O 2 entering the contact lens holder.

Claims (12)

1. A product comprising:

a contact lens holder including one or more contact lenses in a solution,

wherein the solution and the lens include an effective amount of cysteamine or derivatives thereof to treat cystinosis,

wherein the contact lens holder includes at least one barrier layer, wherein each of the barrier layers reduces the amount of O 2 entering the contact lens holder as compared to a contact lens holder without the barrier layer, and

wherein the contact lens holder includes an oil having a lower density than the solution so that the oil forms an oil layer on top of the solution, wherein the oil oil layer has a thickness of 0.5 mm to 2 cm.

2. The product of claim 1 , wherein a space in the contact lens holder not including the contact lenses and the solution is occupied by a gas that is substantially free of O 2 .

3. The product of claim 1 , further comprising a container, wherein the contact lens holder is disposed within the container, wherein an environment within the container is substantially free of O 2 , wherein the container comprises at least one barrier layer, wherein each of the barrier layers reduces the amount of O 2 from entering the container as compared to a container without the barrier layer.

4. The product of claim 3 , wherein the container is a pouch comprising ethylene vinyl alcohol, aluminum foil, and an iron based absorbent layer.

5. The product of claim 1 , wherein the barrier layer includes a layer of ethylene vinyl alcohol, aluminum foil, and an iron based absorbent layer.

6. The product of claim 5 , wherein the at least one barrier layer includes three barrier layers stacked on top of one another.

7. The product of claim 3 , wherein the barrier layer includes a layer of ethylene vinyl alcohol, aluminum foil, and an iron based absorbent layer.

8. The product of claim 7 , wherein the at least one barrier layer includes three barrier layers stacked on top of one another.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2023
From: CHAUHAN, ANUJ; DIXON, PHILLIP J.
To: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
Reel/Frame 065069/0525 →
Continuity (3)
Division 16418061 · May 21, 2019
Provisional Application 62675818 · May 24, 2018
Related Publication 20220347126A1 · Nov 3, 2022