Gliflozins and a method for their delivery during resuscitation from cardiac arrest to improve survival outcomes
A method of performing cardiopulmonary resuscitation on a mammalian subject including the step of delivering an effective amount of a gliflozin solution during cardiac resuscitation through an intravenous or intraosseous route.
1. A method of cardiopulmonary resuscitation on a mammalian subject comprising administering an effective amount of a gliflozin solution to the subject concurrent with cardiac resuscitation.
2. The method of claim 1 wherein the gliflozin is empagliflozin.
3. The method of claim 1 wherein the mammalian subject is human.
4. The method of claim 1 wherein the cardiac resuscitation is mechanical, electrical, chemical, or a combination thereof.
5. The method of claim 1 wherein the cardiopulmonary resuscitation is closed-chest or open-chest.
6. The method of claim 1 wherein the gliflozin is administered by a route selected from the group consisting of intravenous or intraosseous.
7. The method of claim 1 wherein the administration of the gliflozin is in bolus.
8. The method of claim 7 further comprising administering gliflozin continuously through parenteral infusion.
9. The method of claim 8 wherein the bolus injection is performed first followed by the step of parenteral infusion.
10. The method of claim 1 wherein the cardiac arrest is due to ventricular fibrillation, pulseless ventricular tachycardia, pulseless electrical activity, or asystole.