Methods of treating endometrial cancer using hemp extract

1. A method of treatment of endometrial cancer comprising administering to a patient an effective amount of a chemotherapeutic agent selected from the group consisting of: paclitaxel, carboplatin, doxorubicin, cisplatin, docetaxel, gemcitabine, capecitabine, and combinations thereof; and coadministering an effective amount of a composition comprising a cannabis extract (CE), said CE comprising cannabidiol (CBD) at a concentration of between 60% and 99% by weight of the CE and having a pH of between 3.5 and 6, wherein the composition is for intravaginal delivery.

2. The method of claim 1 wherein the chemotherapeutic agent and the CE are administered as one composition or as two different compositions.

3. The method of claim 1 comprising a first step of determining chemoresistance of a cancerous tissue from said patient and administering to the patient an effective amount of the CE upon confirmation of chemoresistance.

4. The method of claim 1 wherein the CE comprises a cannabinoid selected from the group consisting of: Δ-9-tetrahydrocannabinol (Δ 9 -THC), tetrahydrocannabinolic acid (THCA), tetrahydrocannabivarin (THCV), Δ-8-tetrahydrocannabinol (Δ 8 -THC), cannabichromene (CBC), cannabichromene acid (CBCA), cannabigerol (CBG), cannabigerol acid (CBGA), cannabidiolic acid (CBDA), cannabidivarin (CBDV), cannabinol (CBN), cannabicyclol (CBL), and combinations thereof.

5. The method of claim 1 wherein the composition further comprises:

i. at least one of a terpene, a polyphenol, an essential fatty acid, or a phytonutrient;

ii. wherein the terpene is selected from the group consisting: of β-myrcene, β-caryophyllene, linalool, α-pinene, citral, D-limonene, eucalyptol, and combinations thereof;

iii. wherein the polyphenol is selected from the group consisting of catechins, quercetin, cannflavin A/B/C, rutin, chlorogenic acid, and combinations thereof;

iv. wherein the essential fatty acid is selected from the group consisting of: an omega 3, an omega 6, an omega 9, and combinations thereof; and

v. wherein the phytonutrient is selected from the group consisting of: a tocopherol, a sterol, carotene, an aliphatic alcohol, a mineral, and combinations thereof.

6. The method of claim 1 wherein a total concentration of cannabinoids in the CE is between 65% and 99%.

7. The method of claim 1 wherein the composition further comprises at least one additional compound selected from the group consisting of: a terpene, a polyphenol, an essential fatty acid, a phytonutrient, and combinations thereof; and wherein the at least one additional compound makes up between 0.1% and 50% of a total weight of the composition.

8. The method of claim 1 wherein the composition comprises an oil or a fat as a carrier.