Diagnostic methods and devices for controlling acute glycemia

1. A device for tracking and forecasting glycemic levels in a patient, said device comprising:

a housing;

a processor coupled to a memory;

a display configured to display a user interface and operatively connected to said processor, wherein the user interface is configured to receive at least one input from a user; and

a port configured to receive a blood glucose monitoring strip, or needle prick, or skin fluids pump, wherein said device is configured to receive a blood glucose related sample from a patient and

a transducer operatively connected to said port and configured to generate blood glucose values from blood glucose samples of the patient taken over a period of time;

wherein said processor, said display, said port and said transducer are contained in said housing, and

wherein said processor is configured with machine-executable instructions to: receive a time-ordered sequence of blood glucose values taken over a defined period of time from the transducer,

calculate at least one quantile of said time-ordered sequence of blood glucose values taken over the period of time, calculate an orbit centroid by weighted averaging said time-ordered sequence of blood glucose quantile values taken over an increasing sequence of time-ordered periods of time of at least one quantile,

create a Lorenz phase plot of the at least one quantile time-ordered sequence of blood glucose values by plotting a blood glucose quantile value in the at least one quantile sequence as a function of an immediate previous blood glucose quantile value in said at least one quantile sequence, wherein the Lorenz phase plot defines an orbit which flows about the orbit centroid and wherein the orbit is defined as a series of adjacent vectors each connecting a blood glucose quantile value with a previous blood glucose quantile value and each adjacent vector comprising a vector coordinate, identify a probability trend for acute glycemia by applying a quantitative model to the orbit defined in the Lorenz phase plot, identify a risk of impeding acute glycemia by determining vector position and a change in an angle between said adjacent vectors and a direction of said change, and

wherein the device is configured to display the created Lorenz phase plot, the identified probability trend for acute glycemia and a notification of the risk of impending acute glycemia event based on the identified vector position and change in the angle and the direction of said change, wherein a change in the angle of −60 degrees indicates a risk of acute glycemia within 24 hours, as further indicated by a previous orbital section with recurrent position proximal to the said orbital position.

2. The device of claim 1 , wherein the calculated at least one quantile comprises a Q98 quantile or a Q02 quantile or a combination thereof.

3. The device of claim 2 , wherein the impending acute glycemia comprises an impending hypoglycemia event or an impending hyperglycemia event.

4. The device of claim 3 , wherein said processor is configured to identify and forecast, days in which extreme glycemia was experienced by the patient and wherein said display is configured to display the days in which said extreme glycemia was experienced by the patient.

5. The device of claim 4 , wherein the period of time includes a 24-hour day and wherein the processor is configured to identify and forecast days within the sequence of multiple days in which the patient will experience acute glycemia.