IP Library › Granted Patent US 11,806,175
Granted Patent B2
US 11,806,175 · App. 17/642,725 · Granted Nov 7, 2023

Few-view CT image reconstruction system

Inventors: Huidong Xie (Troy, NY); Ge Wang (Loudonville, NY); Hongming Shan (Troy, NY); Wenxiang Cong (Albany, NY)
Assignee: Rensselaer Polytechnic Institute
A61B6/032A61B6/5205G06T11/005G06T11/006G06T2211/421G06T2211/436
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Quick Facts
Patent No.
US 11,806,175
App. No.
17/642,725
Granted
Nov 7, 2023
Kind
B2
Abstract

A system for few-view computed tomography (CT) image reconstruction is described. The system includes a preprocessing module, a first generator network, and a discriminator network. The preprocessing module is configured to apply a ramp filter to an input sinogram to yield a filtered sinogram. The first generator network is configured to receive the filtered sinogram, to learn a filtered back-projection operation and to provide a first reconstructed image as output. The first reconstructed image corresponds to the input sinogram. The discriminator network is configured to determine whether a received image corresponds to the first reconstructed image or a corresponding ground truth image. The generator network and the discriminator network correspond to a Wasserstein generative adversarial network (WGAN). The WGAN is optimized using an objective function based, at least in part, on a Wasserstein distance and based, at least in part, on a gradient penalty.

Claims (39)

1. A few-view computed tomography (CT) image reconstruction system, the system comprising:

a preprocessing module configured to apply a ramp filter to an input sinogram to yield a filtered sinogram;

a first generator network configured to receive the filtered sinogram, to learn a filtered back-projection operation and to provide a first reconstructed image as an output, the first reconstructed image corresponding to the input sinogram; and

a discriminator network configured to determine whether a received image corresponds to the first reconstructed image or a corresponding ground truth image, the first generator network and the discriminator network corresponding to a Wasserstein generative adversarial network (WGAN), the WGAN optimized using an objective function based, at least in part, on a Wasserstein distance and based, at least in part, on a gradient penalty.

2. The system of claim 1 , further comprising a second generator network configured to receive a concatenation of the first reconstructed image and a filtered back-projection of the input sinogram and to provide a second reconstructed image, the discriminator network further configured to determine whether the received image corresponds to the second reconstructed image.

3. The system of claim 2 , wherein the second generator network corresponds to a refinement portion.

4. The system of claim 2 , further comprising a filtered back projection module configured to receive the input sinogram and to provide the filtered back-projection of the input sinogram.

5. The system of claim 1 , wherein the first generator network is configured to learn the filtered back-projection operation in a point-wise manner.

6. The system of claim 1 , wherein the first generator network comprises a filtration portion, a back-projection portion, and a refinement portion.

7. The system of claim 1 , wherein the WGAN is trained, initially, using image data from an image database comprising a plurality of images.

8. The system of claim 1 , wherein the first generator network is configured to reconstruct the first reconstructed image using O(C×N×N,) parameters, where N is a dimension of the first reconstructed image, N, is a number of projections, and C is an adjustable hyper-parameter in the range of 1 to N.

9. A method for few-view computed tomography (CT) image reconstruction, the method comprising:

applying, by a preprocessing module, a ramp filter to an input sinogram to yield a filtered sinogram;

receiving, by a first generator network, the filtered sinogram;

learning, by the first generator network, a filtered back-projection operation;

providing, by the first generator network, a first reconstructed image as an output, the first reconstructed image corresponding to the input sinogram; and

determining, by a discriminator network, whether a received image corresponds to the first reconstructed image or a corresponding ground truth image, the first generator network and the discriminator network corresponding to a Wasserstein generative adversarial network (WGAN), the WGAN optimized using an objective function based, at least in part, on a Wasserstein distance and based, at least in part, on a gradient penalty.

10. The method of claim 9 , further comprising:

receiving, by a second generator network, a concatenation of the first reconstructed image and a filtered back-projection of the input sinogram;

providing, by the second generator network, a second reconstructed image; and

determining, by the discriminator network, whether the received image corresponds to the second reconstructed image.

11. The method of claim 10 , further comprising receiving, by a filtered back projection module, the input sinogram and providing, by the filtered back projection module, the filtered back-projection of the input sinogram.

12. The method of claim 9 , wherein the first generator network is configured to learn the filtered back-projection operation in a point-wise manner.

13. The method of claim 9 , wherein the first generator network comprises a filtration portion, a back-projection portion, and a refinement portion.

14. The method of claim 9 , further comprising learning, by the first generator network, an initial filtered back-projection operation using image data from an image database comprising a plurality of images.

15. The method of claim 9 , wherein the first generator network is configured to reconstruct the first reconstructed image using O(C×N×N,) parameters, where N is a dimension of the first reconstructed image, N, is a number of projections, and C is an adjustable hyper-parameter in the range of 1 to N.

16. A computer readable storage device having stored thereon instructions configured for a few-view computed tomography (CT) image reconstruction, the instructions that when executed by one or more processors result in the following operations comprising:

applying a ramp filter to an input sinogram to yield a filtered sinogram;

receiving the filtered sinogram;

learning a filtered back-projection operation;

providing a first reconstructed image as an output, the first reconstructed image corresponding to the input sinogram; and

determining whether a received image corresponds to the first reconstructed image or a corresponding ground truth image, the operations corresponding to a Wasserstein generative adversarial network (WGAN), the WGAN optimized using an objective function based, at least in part, on a Wasserstein distance and based, at least in part, on a gradient penalty.

17. The device of claim 16 , wherein the instructions that when executed by the one or more processors result in the following additional operations comprising:

receiving a concatenation of the first reconstructed image and a filtered back-projection of the input sinogram;

providing a second reconstructed image; and

determining whether the received image corresponds to the second reconstructed image.

18. The device of claim 16 , wherein the filtered back-projection operation is learned in a point-wise manner.

19. The device of claim 16 , wherein the instructions that when executed by the one or more processors result in the following additional operations comprising learning an initial filtered back-projection operation using image data from an image database comprising a plurality of images.

20. The device of claim 16 , wherein the first reconstructed image is reconstructed using O(C×N×N,) parameters, where N is a dimension of the first reconstructed image, N, is a number of projections, and C is an adjustable hyper-parameter in the range of 1 to N.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 22, 2022
From: XIE, HUIDONG; WANG, GE; SHAN, HONGMING; CONG, WENXIANG
To: RENSSELAER POLYTECHNIC INSTITUTE
Reel/Frame 059338/0688 →
Continuity (3)
Provisional Application 62899517 · Sep 12, 2019
Provisional Application 63077745 · Sep 14, 2020
Related Publication 20220375142A1 · Nov 24, 2022
Cited By (1)
US 12,657,797