Urolithin derivatives and methods of use thereof

Inventors: Christopher L. Rinsch (Lausanne, CH); Penelope Andreux (Eclepens, CH); Jonathan Mark Sutton (Harlow, GB); Eileen Mary Seward (Harlow, GB); Jamie D. Knight (Harlow, GB); Ian Linney (London, GB); Peter C. Sennhenn (Munich, DE); Said Oumouch (Wittenheim, FR); Florent Beaufils (Bartenheim, FR); Thomas Christian Fessard (Küsnacht, CH)

Assignee: Vandria SA

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Abstract

Disclosed are compounds, compositions, and methods useful for treating neuronal and mitochondrial diseases.

Claims (9)

1. A compound selected from:

or a pharmaceutically acceptable salt thereof.

2. The compound of claim 1 having the structure:

or a pharmaceutically acceptable salt thereof.

3. The compound of claim 1 having the structure:

or a pharmaceutically acceptable salt thereof.

4. A pharmaceutical composition comprising a compound of claim 1 ; and a pharmaceutically acceptable carrier.

5. A pharmaceutical composition comprising a compound of claim 2 ; and a pharmaceutically acceptable carrier.

6. A pharmaceutical composition comprising a compound of claim 3 ; and a pharmaceutically acceptable carrier.

Assignments (7)

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2023

From: SPIROCHEM AG

To: VANDRIA SA

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2023

From: OUMOUCH, SAID; BEAUFILS, FLORENT; FESSARD, THOMAS CHRISTIAN

To: SPIROCHEM AG