IP Library › Granted Patent US 11,826,098
Granted Patent B2
US 11,826,098 · App. 16/345,632 · Granted Nov 28, 2023

System and method for the treatment of amblyopia

Inventors: Eric Gaier (Boston, MA); Dean Travers (Cambridge, MA); Scott Xiao (Cambridge, MA)
Assignee: Massachusetts Eye and Ear Infirmary
A61B3/028A61B3/0058G02B27/005
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Quick Facts
Patent No.
US 11,826,098
App. No.
16/345,632
Granted
Nov 28, 2023
Kind
B2
Abstract

A system and methods for the treatment of amblyopia are described. The system includes a display system capable of in delivering a second image to a second eye of a patient and a first image to a first eye of a patient. The system also includes a controller in capable of delaying the delivery of the second image to the second eye of the patent. The controller is configured to receive the second image and the first image. The controller is also configured to identify a delay factor associated with the second image. The controller is also configured to provide the first image to the display system for viewing by the first eye of the patient. The controller is also configured such that after a delay determined by the delay factor, the controller provides the second image to the display system for viewing by the second eye of the patient.

Claims (18)

1. A method comprising:

receiving, at a controller comprising one or more processing devices, a first image and a second image;

identifying, by the controller, a delay factor associated with the second image;

presenting, by the controller, the first image on a portion of a display device visible to the first eye of a subject;

delivering, by the controller in accordance with the delay factor, the second image to the second eye of the subject, wherein at least a portion of the second image is delivered 1-1000 msec before or after the first image, the second image being visible to the second eye concurrently with the first image being visible to the first eye,

wherein a contrast of the second image is altered such that the contrast of the second image is different from a contrast of the first image, and

wherein the delay factor is identified based on measuring one or more parameters at each of multiple candidate delay factors.

2. The method of claim 1 , wherein the first eye or the second eye is amblyopic.

3. The method of claim 1 , wherein the display device comprises a single display, and the first image and the second image are presented through the single display and selectively filtered to each eye.

4. The method of claim 3 , wherein the single display uses polarization to selectively deliver the first image and the second image, or chromatic filters to selectively deliver the first image and the second image.

5. The method of claim 1 , wherein the display device comprises two separate displays, and the first image and the second image are presented through the separate displays.

6. The method of claim 1 , wherein the first image and the second image are part of a virtual reality experience or part of an augmented reality experience.

7. The method of claim 1 , wherein the one or more parameters comprise an electrophysiologic metric measured from visually evoked potential (VEP).

8. The method of claim 1 , wherein the delay factor is determined at least in part using at least one of at least one of eye tracking technologies, game-based tests of binocularity or inter-ocular suppression.

9. The method of claim 1 , wherein the delay factor is determined at least in part through testing a plurality of delay times, each delay time measured to determine a corresponding response and the delay factor is selected from the plurality of delay times based on measured improvements to binocularity.

10. The method of claim 1 , wherein delivering at least a portion of the second image 1-1000 msec before or after the first image comprises delaying delivery of only a subpart of the second image.

11. The method of claim 1 , wherein the display device comprises a single split display presented or projected to each eye, and the first image and the second image are presented through the single split display.

12. The method of claim 1 , wherein the one or more parameters comprise an electrophysiologic metric measured from electroencephalography (EEG).

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 13, 2020
From: GAIER, ERIC
To: MASSACHUSETTS EYE AND EAR INFIRMARY
Reel/Frame 051488/0994 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 7, 2020
From: TRAVERS, DEAN; XIAO, SCOTT
To: LUMINOPIA, INC.
Reel/Frame 051436/0937 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 7, 2020
From: LUMINOPIA, INC.
To: MASSACHUSETTS EYE AND EAR INFIRMARY
Reel/Frame 051437/0006 →
Continuity (3)
Provisional Application 62448479 · Jan 20, 2017
Provisional Application 62416355 · Nov 2, 2016
Related Publication 20200054205A1 · Feb 20, 2020