System and method for crimping a prosthetic valve

1. A device for crimping a radially expandable and compressible prosthetic valve, the device comprising:

a housing configured to receive a prosthetic valve in a radially expanded state, the housing comprising an outlet and a funnel segment in communication with the outlet;

a pusher member configured to move axially through the housing and abut the prosthetic valve within the housing, the pusher member comprising an outer groove; and

an actuator rotatably coupled to the housing and pusher member, the actuator comprising an inwardly extending ledge received by and configured to rotate within the outer groove of the pusher member;

wherein rotation of the actuator relative to the housing and pusher member moves the pusher member and prosthetic valve axially through and relative to the housing such that at least a portion of the prosthetic valve radially compresses through engagement with the funnel segment and exits the outlet of the housing.

2. The device of claim 1 , wherein the pusher member comprises a lip configured to deflect inwardly to allow the ledge of the actuator to be removed from the outer groove of the pusher member for separating the actuator from the pusher member.

3. The device of claim 1 , wherein the actuator encircles the pusher member.

4. The device of claim 1 , wherein the housing encircles the pusher member.

5. The device of claim 1 , wherein the actuator is threadably coupled to the housing.

6. The device of claim 1 , wherein the pusher member comprises an internal cavity and an annular lip configured to retain the prosthetic valve as the pusher member and prosthetic valve move axially through and relative to the housing.

7. The device of claim 1 , wherein the pusher member comprises a plurality of radially extending fins.

8. The device of claim 1 , wherein the housing comprises an inner surface and a plurality of circumferentially spaced ribs extending radially inwardly from the inner surface that are configured to radially compress at least a portion of the prosthetic valve.

9. The device of claim 8 , wherein each rib of the housing has a width that increases from one end portion of the housing to another end portion of the housing.

10. The device of claim 1 , wherein the pusher member and the housing comprise complementary features that restrict relative rotation between the pusher member and the housing when the pusher member moves through the housing.

11. The device of claim 10 , wherein the feature of the pusher member comprises at least one external protrusion and the feature of the housing comprises at least one slot to engage the external protrusion, wherein engagement between the external protrusion and the slot restricts relative rotation between the pusher member and the housing.

12. A device for crimping a radially expandable and compressible prosthetic valve, the device comprising:

a housing configured to receive a prosthetic valve in a radially expanded state, the housing comprising an outlet and a funnel segment in communication with the outlet;

a pusher member configured to move axially through the housing and abut the prosthetic valve within the housing, the pusher member comprising a pair of releasable locking features; and

an actuator rotatably coupled to the housing and the pusher member, the actuator comprising an inwardly extending annular ledge;

wherein the locking features of the pusher member releasably engage the annular ledge of the actuator and the actuator is configured to rotate relative to the locking features;

wherein rotation of the actuator relative to the housing and pusher member moves the pusher member and prosthetic valve axially through and relative to the housing such that at least a portion of the prosthetic valve radially compresses through engagement with the funnel segment and exits the outlet of the housing.

13. The device of claim 12 , wherein the locking features are diametrically opposed to one another.

14. The device of claim 12 , wherein the locking features of the pusher member extend through an opening defined by the annular ledge of the actuator.

15. The device of claim 12 , wherein the locking features comprise a deflectable lip and a notch configured to receive the annular ledge of the actuator.

16. The device of claim 12 , wherein the pusher member comprises a longitudinally extending external rib and the housing comprises a longitudinally extending slot configured to receive the external rib to limit relative rotation between the pusher member and the housing.

17. The device of claim 12 , wherein a portion of the housing is disposed between the pusher member and the actuator.

18. A device for crimping a radially expandable and compressible prosthetic valve, the device comprising:

a housing assembly configured to receive a prosthetic valve in a radially expanded state, the housing assembly comprising a first housing component and a second housing component separably coupled to the first housing component, wherein when the first and second housing components are coupled to each other, the first and second housing components form an outlet and a funnel segment of the housing assembly that are in communication with one another;

a retaining member encircling the housing assembly and configured to releasably retain the first and second housing components to one another; and

a valve holder configured to extend into and move axially through the housing assembly and abut the prosthetic valve within the housing assembly, wherein as the valve holder moves axially through and relative to the housing assembly at least a portion of the prosthetic valve compresses radially and exits the outlet of the housing assembly.

19. The device of claim 18 , wherein one of the first and second housing components comprises a protrusion and the other of the first and second housing components comprises a recess configured to mate with the protrusion.

20. The device of claim 18 , further comprising an actuator rotatably coupled to the housing assembly and the valve holder, and wherein the actuator is configured such that when the actuator is rotated relative to the housing assembly and the valve holder, the actuator moves the valve holder and the prosthetic valve axially through and relative to the housing assembly such that the prosthetic valve engages the funnel segment.