Dermal patch for collecting a physiological sample
A dermal patch for collecting a physiological sample includes a housing with a collection chamber, a sample channel and a pin within a receptacle of the housing. The sample channel is configured to direct a physiological sample drawn from a subject to the collection chamber. The pin is removably positioned within the receptacle and is configured to move from an undeployed position to a deployed position. The pin is configured to seal the receptacle when in the undeployed position and is further configured to facilitate generation of negative pressure in the sample channel when the pin is moved from the undeployed to the deployed position.
1. A system comprising:
a dermal patch comprising a housing configured to attach to a subject's skin,
wherein the housing includes an opening to provide access to the subject's skin when the dermal patch is attached to the subject's skin;
a lancet configured to engage with the opening, wherein the lancet includes a needle movable from an undeployed position to a deployed position, and wherein in the deployed position, the needle is configured to puncture the skin to draw a physiological sample; and
a fluid pouch coupled to the housing, wherein the fluid pouch is configured to store a processing fluid and wherein the fluid pouch is formed of a frangible membrane; and
a slider coupled to the housing, wherein the housing further includes a puncture element, and wherein the slider is configured to compress the fluid pouch into the puncture element to rupture the fluid pouch.
2. A system comprising:
a dermal patch comprising a housing configured to attach to a subject's skin,
wherein the housing includes an opening to provide access to the subject's skin when the dermal patch is attached to the subject's skin;
a lancet configured to engage with the opening, wherein the lancet includes a needle movable from an undeployed position to a deployed position, and wherein in the deployed position, the needle is configured to puncture the skin to draw a physiological sample;
a moveable pin disposed within the housing, wherein the pin is configured to generate a vacuum within the housing when moved, and wherein the vacuum generated by the pin is proportional to the movement of the pin; and
a receptacle, wherein the pin is disposed within the receptacle, and wherein the pin is configured to seal the receptacle.
3. The system of claim 2 , wherein the housing further includes:
a chamber configured to receive the drawn physiological sample, and
a channel in open communication with the chamber and the receptacle,
wherein the pin is configured to generate the vacuum within the channel to draw the drawn physiological sample to the chamber.