IP Library Granted Patent US 11,915,828
Granted Patent B2
US 11,915,828 · App. 16/891,305 · Granted Feb 27, 2024

System and method of using machine learning for extraction of symptoms from electronic health records

Inventor: Charlotta Lindvall (Chestnut Hill, MA)
Assignee: DANA-FARBER CANCER INSTITUTE, INC.
G16H50/20G06F40/295G16H10/60G16H20/00G16H50/30G16H70/60
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Quick Facts
Patent No.
US 11,915,828
App. No.
16/891,305
Granted
Feb 27, 2024
Kind
B2
Abstract

A method for autonomously identifying symptom terms in free running text data includes the acts of defining a plurality of symptom terms associated with a particular pathology or therapeutic substance or procedure, labeling in a text data set any defined symptom terms and associating a tag indicating any of a positive, negative, or other status with relation to the labeled symptom term, and processing with a natural language processing algorithm multiple different subsets of the text data containing labeled symptom terms to identify a frequency of occurrence of a symptom term and to improve identification accuracy.

Claims (38)

1. A method for identifying a symptom in text data comprising:

A) processing a plurality of free-running text into a segmented text data set;

B) labeling words in the segmented text data set, including one or more symptom terms each associated with a specific symptom and associating a tag and a position with a labeled word, the tag indicating any of a positive, negative, or neutral value relative to the symptom term, wherein a positive value indicates a presence of a symptom term and wherein a negative value indicates an absence of a symptom term and wherein a neutral value indicates no relationship to a symptom term;

C) processing, with the natural language processing algorithm, a first subset of the text data set containing labeled symptom terms; and

D) processing, with the natural language processing algorithm, a second subset of the text data set containing labeled symptom terms.

2. The method of claim 1 further comprising:

E) processing, with the natural language processing algorithm, a third subset of the text data containing labeled symptom terms.

3. The method of claim 1 further comprising:

E) following D), processing, with the natural language processing algorithm, another text data set not containing labeled symptom terms.

4. The method of claim 3 further comprising:

E) correlating a frequency of a labeled symptom term having a tag indicating a positive status with any of a pathology, therapeutic substance, therapeutic procedure, or therapeutic device.

5. The method of claim 1 wherein B) comprises:

B1) labeling another term in a same segment of the text data set as an attribute of a labeled symptom term, if the another term describes any of a negation, frequency, severity, change or interference with a symptom identified by the labeled symptom term.

6. The method of claim 5 wherein the other correlation status with the symptom term is context-dependent status.

7. The method of claim 1 wherein the other correlation status with the symptom term is a neutral status.

8. The method of claim 1 wherein a symptom term or another term comprises any of a single word, multiple words, number, acronym, graphic element or any combination thereof.

9. The method of claim 1 wherein the plurality of symptom terms are associated with any of a pathology, therapeutic substance, therapeutic procedure, or therapeutic device.

10. The method of claim 1 wherein C) comprises processing the first subset of the text data with any of a Conditional Random Field Model process.

11. The method of claim 1 wherein D) comprises processing the first subset of the text data with a Conditional Random Field Model process.

12. A method for identifying a symptom in text data comprising:

A) defining a plurality of symptom terms;

B) selecting a text data set including at least a subset of the plurality of defined symptom terms;

C) labeling, in the text data set, defined symptom terms and associating a position of the labeled symptom term within the text data set and further associating a tag indicating any of a positive, negative, or neutral value relative to the labeled symptom term, wherein a positive value indicates a presence of a symptom term and wherein a negative value indicates an absence of a symptom term and wherein a neutral value indicates no relationship to a symptom term;

D) processing, with multiple natural language processing algorithms, a first subset of the text data set containing labeled symptom terms to identify a frequency of occurrences of a symptom term in the first subset of the text data;

E) scoring accuracy of the multiple natural language processing algorithms in processing the first subset of the text data; and

F) processing, with a natural language processing algorithm having greatest accuracy in step E), a second subset of the text data set containing labeled symptom terms.

13. The method of claim 12 further comprising:

G) processing, with the natural language processing algorithm, a third subset of the text data containing labeled symptom terms.

14. The method of claim 12 further comprising:

G) following F), processing, with the natural language processing algorithm, another text data set not containing labeled symptom terms.

15. The method of claim 14 further comprising:

G) correlating a frequency of a labeled symptom term having a tag indicating a positive status with any of a pathology, therapeutic substance, therapeutic procedure, or therapeutic device.

16. The method of claim 12 wherein C) comprises:

C1) labeling another term in the text data set as an attribute of a labeled symptom term, if the another term describes any of a negation, frequency, severity, change or interference with a symptom identified by the labeled symptom term.

17. The method of claim 16 wherein the other correlation status with the symptom term is context-dependent status.

18. The method of claim 12 wherein the other status with the symptom term is a neutral status.

19. The method of claim 12 wherein one of the symptom term or another term comprises any of a single word, multiple words, number, acronym, graphic element or any combination thereof.

20. The method of claim 12 wherein the plurality of symptom terms are associated with any of a pathology, therapeutic substance, therapeutic procedure, or therapeutic device.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 16, 2020
From: LINDVALL, CHARLOTTA
To: DANA-FARBER CANCER INSTITUTE, INC.
Reel/Frame 054074/0586 →
Continuity (2)
Provisional Application 62856832 · Jun 4, 2019
Related Publication 20200388396A1 · Dec 10, 2020
Cited By (1)
US 12,555,566