Ingestible films having substances from hemp or cannabis
View Patent ↗Films that are mucosally dissolvable, and containing a matrix and one or more active agents from hemp or cannabis within the matrix, are provided. The disclosure also provides methods for preparing such a film for pharmaceutical and nutraceutical applications.
1. An emulsion consisting essentially of:
water;
a component selected from the group consisting of cannabis sativa extract, cannabis sativa oil, and combinations thereof;
a component selected from the group consisting of pullulan, cellulose, sodium carboxymethylcellulose, microcrystalline cellulose, polyvinylpyrrolidone, sodium alginate, and combinations thereof;
a component selected from the group consisting of glycerin, diglycerin, coconut oil, medium chain triglycerides, and combinations thereof;
a component selected from the group consisting of polysorbate 80, lecithin, xanthan gum, tapioca starch, carrageenan, and combinations thereof;
a component selected from the group consisting of sucralose, stevia plant extract, acesulfame potassium, monk fruit, dextrose, sucrose, and combinations thereof;
a component selected from the group consisting of potassium sorbate, sodium benzoate, sorbitol, calcium carbonate, sorbitan monostearate, sorbitan stearate, and combinations thereof; and
a component selected from the group consisting of cinnamon oil, wintergreen oil, peppermint oil, clove oil, bay oil, anise oil, eucalyptus oil, thyme oil, cedar leaf oil, nutmeg oil, sage oil, bitter almond oil, cassia oil, vanilla, lemon oil, orange oil, grape oil, lime oil, grapefruit oil, apple oil, pear oil, peach oil, strawberry oil, raspberry oil, cherry oil, plum oil, pineapple oil, apricot oil, lemon, lime, orange, mango, grape, apple, pear, peach, strawberry, raspberry, cherry, plum, apricot, mint, chocolate, marshmallow, bubble gum, peanut butter, ginger, licorice, chicken flavor, beef flavor, fish flavor, menthol, thiamin, riboflavin, nicotinic acid, pantothenic acid, pyridoxine, biotin, folic acid, cobalamin, zinc, L-arginine, lipoic acid, ascorbic acid, citric acid, retinol, calciferol, melatonin, bee pollen, bran, cellulose fiber, wheat germ, kelp, cod liver oil, ginseng , fish oil, tartrazine, and combinations thereof.
2. The emulsion of claim 1 , wherein the emulsion is at least partially contained within a mucosally dissolvable film.
3. The emulsion of claim 1 consisting essentially of:
water;
cannabis sativa extract;
pullulan;
a component selected from the group consisting of glycerin, medium chain triglycerides, and combinations thereof;
a component selected from the group consisting of lecithin, xanthan gum, carrageenan, and combinations thereof;
stevia plant extract;
potassium sorbate; and
a component selected from the group consisting of cinnamon oil, wintergreen oil, peppermint oil, clove oil, bay oil, anise oil, eucalyptus oil, thyme oil, cedar leaf oil, nutmeg oil, sage oil, bitter almond oil, cassia oil, vanilla, lemon oil, orange oil, grape oil, lime oil, grapefruit oil, apple oil, pear oil, peach oil, strawberry oil, raspberry oil, cherry oil, plum oil, pineapple oil, apricot oil, lemon, lime, orange, mango, grape, apple, pear, peach, strawberry, raspberry, cherry, plum, apricot, mint, chocolate, marshmallow, bubble gum, peanut butter, ginger, licorice, chicken flavor, beef flavor, fish flavor, riboflavin, pyridoxine, folic acid, cobalamin, zinc, L-arginine, citric acid, and combinations thereof.
4. The emulsion of claim 3 , wherein the emulsion is at least partially contained within a mucosally dissolvable film.
5. The emulsion of claim 1 consisting essentially of:
water;
a component selected from the group consisting of cannabis sativa extract, cannabis sativa oil, and combinations thereof;
a component selected from the group consisting of pullulan, sodium alginate, and combinations thereof;
a component selected from the group consisting of glycerin, diglycerin, medium chain triglycerides, and combinations thereof;
a component selected from the group consisting of polysorbate 80, tapioca starch, and combinations thereof;
a component selected from the group consisting of sucralose, dextrose, sucrose, and combinations thereof;
a component selected from the group consisting of sorbitol, sorbitan monostearate, and combinations thereof; and
a component selected from the group consisting of cinnamon oil, wintergreen oil, peppermint oil, clove oil, bay oil, anise oil, eucalyptus oil, thyme oil, cedar leaf oil, nutmeg oil, sage oil, bitter almond oil, cassia oil, vanilla, lemon oil, orange oil, grape oil, lime oil, grapefruit oil, apple oil, pear oil, peach oil, strawberry oil, raspberry oil, cherry oil, plum oil, pineapple oil, apricot oil, lemon, lime, orange, mango, grape, apple, pear, peach, strawberry, raspberry, cherry, plum, apricot, mint, chocolate, marshmallow, bubble gum, peanut butter, ginger, licorice, chicken flavor, beef flavor, fish flavor, menthol, cellulose fiber, and combinations thereof.
6. The emulsion of claim 5 , wherein the emulsion is at least partially contained within a mucosally dissolvable film.
7. The emulsion of claim 1 consisting essentially of:
water;
cannabis sativa oil;
sodium carboxymethylcellulose;
a component selected from the group consisting of glycerin, coconut oil, and combinations thereof;
xanthan gum;
monk fruit;
calcium carbonate; and
a component selected from the group consisting of cinnamon oil, wintergreen oil, peppermint oil, clove oil, bay oil, anise oil, eucalyptus oil, thyme oil, cedar leaf oil, nutmeg oil, sage oil, bitter almond oil, cassia oil, vanilla, lemon oil, orange oil, grape oil, lime oil, grapefruit oil, apple oil, pear oil, peach oil, strawberry oil, raspberry oil, cherry oil, plum oil, pineapple oil, apricot oil, lemon, lime, orange, mango, grape, apple, pear, peach, strawberry, raspberry, cherry, plum, apricot, mint, chocolate, marshmallow, bubble gum, peanut butter, ginger, licorice, chicken flavor, beef flavor, fish flavor, menthol, and combinations thereof.
8. The emulsion of claim 7 , wherein the emulsion is at least partially contained within a mucosally dissolvable film.
9. The emulsion of claim 1 consisting essentially of:
water;
a component selected from the group consisting of cannabis sativa extract, cannabis sativa oil, and combinations thereof;
sodium alginate;
a component selected from the group consisting of glycerin, medium chain triglycerides, and combinations thereof;
a component selected from the group consisting of polysorbate 80, tapioca starch, and combinations thereof;
a component selected from the group consisting of sucralose, sucrose, and combinations thereof;
a component selected from the group consisting of sorbitol, sorbitan stearate, and combinations thereof; and
a component selected from the group consisting of cinnamon oil, wintergreen oil, peppermint oil, clove oil, bay oil, anise oil, eucalyptus oil, thyme oil, cedar leaf oil, nutmeg oil, sage oil, bitter almond oil, cassia oil, vanilla, lemon oil, orange oil, grape oil, lime oil, grapefruit oil, apple oil, pear oil, peach oil, strawberry oil, raspberry oil, cherry oil, plum oil, pineapple oil, apricot oil, lemon, lime, orange, mango, grape, apple, pear, peach, strawberry, raspberry, cherry, plum, apricot, mint, chocolate, marshmallow, bubble gum, peanut butter, ginger, licorice, chicken flavor, beef flavor, fish flavor, menthol, cellulose fiber, tartrazine, and combinations thereof.
10. The emulsion of claim 9 , wherein the emulsion is at least partially contained within a mucosally dissolvable film.
11. The emulsion of claim 1 consisting essentially of:
water;
a component selected from the group consisting of cannabis sativa extract, cannabis sativa oil, and combinations thereof;
pullulan;
a component selected from the group consisting of glycerin, medium chain triglycerides, and combinations thereof;
a component selected from the group consisting of polysorbate 80, tapioca starch, and combinations thereof;
sucralose;
sorbitan monostearate; and
a component selected from the group consisting of cinnamon oil, wintergreen oil, peppermint oil, clove oil, bay oil, anise oil, eucalyptus oil, thyme oil, cedar leaf oil, nutmeg oil, sage oil, bitter almond oil, cassia oil, vanilla, lemon oil, orange oil, grape oil, lime oil, grapefruit oil, apple oil, pear oil, peach oil, strawberry oil, raspberry oil, cherry oil, plum oil, pineapple oil, apricot oil, lemon, lime, orange, mango, grape, apple, pear, peach, strawberry, raspberry, cherry, plum, apricot, mint, chocolate, marshmallow, bubble gum, peanut butter, ginger, licorice, chicken flavor, beef flavor, fish flavor, menthol, cellulose fiber, and combinations thereof.
12. The emulsion of claim 11 , wherein the emulsion is at least partially contained within a mucosally dissolvable film.