IP Library › Granted Patent US 11,957,936
Granted Patent B2
US 11,957,936 · App. 15/931,370 · Granted Apr 16, 2024

Passive wire reflectors for improved image quality in MR-guided focused ultrasound

Inventors: Xinqiang Yan (Nashville, TN); William A. Grissom (Nashville, TN)
Assignee: Vanderbilt University
A61N7/02A61B5/0036A61B5/055G01R33/34038G01R33/4814A61N2007/0021G06T2207/10088
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Quick Facts
Patent No.
US 11,957,936
App. No.
15/931,370
Granted
Apr 16, 2024
Kind
B2
Abstract

A system for transcranial magnetic resonance (MR)-guided focused ultrasound and method of using transcranial MR-guided focused ultrasound are disclosed. The system includes a transcranial ultrasound transducer configured to apply ultrasound radiation to a patient's head. The system also includes an antenna that reflects radio frequency (RF) waves. The antenna is configured to be positioned between the transducer and the patient's head. The antenna and at least a portion of the patient's head are surrounded by a fluid. Embodiments foster improved MR image quality scans of the patient's head when the transducer is filled with the fluid.

Claims (51)

1. A system for transcranial magnetic resonance (MR)-guided focused ultrasound, the system comprising:

a transcranial ultrasound transducer configured to apply ultrasound radiation to a head of a patient, the transcranial ultrasound transducer comprising:

a housing defining a cavity that is configured to receive the head of the patient; and

a transducer surface within the housing;

an antenna that is configured to reflect radio frequency (RF) waves; and

a support configured to be connected to the transcranial ultrasound transducer and configured to suspend the antenna within the cavity, wherein: the support configured to support the antenna at a position at which,

when the head is received within the cavity, the antenna is positioned entirely within the cavity between the housing and the head, and

the antenna is passive and does not form an electrical connection.

2. The system of claim 1 , wherein the antenna comprises two crossed wires.

3. The system of claim 1 , wherein the antenna comprises one or more wires, the one or more wires being configured in at least one of a crossed pattern, a figure-eight pattern, a circular shape, a concentric, non-connected circular arrangement, or multiple strands.

4. The system of claim 1 , further comprising a fluid surrounding the antenna and configured to surround the head when the head is received within the cavity.

5. The system of claim 4 , wherein the fluid is water.

6. The system of claim 4 , wherein the antenna is suspended in the fluid via the support.

7. The system of claim 1 , further comprising an MR device configured to image the head while the ultrasound radiation is applied by the transcranial ultrasound transducer to the head.

8. The system of claim 7 , wherein the MR device comprises a transmission coil that is configured to emit primary RF waves, and

when the primary RF waves are emitted from the transmission coil the antenna is configured to generate electrical currents that reflect secondary RF waves and to cause the secondary RF waves to propagate away from the antenna.

9. The system of claim 8 , wherein the antenna and the transcranial ultrasound transducer are configured to combine the primary RF waves and the secondary RF waves inside the head to produce a total field for MR excitation.

10. The system of claim 9 , wherein the MR device comprises an MR receiver coil that is configured to receive the primary RF waves from the head during signal reception by the MR device.

11. The system of claim 10 , wherein

the antenna is configured to generate the secondary RF waves and to propagate the secondary RF waves away from the antenna when the primary RF waves are emitted from the head during the signal reception by the MR device, and

the MR device is configured to combine the primary RF waves and the secondary RF waves together in the MR device.

12. The system of claim 1 , wherein

the housing is concave and comprises an inner surface,

the cavity comprises a bottom opening, and

the antenna is positioned within the cavity between the inner surface and the bottom opening and is configured to reflect RF waves entering the cavity from the bottom opening before the RF waves reach the inner surface.

13. The system of claim 12 , wherein the support is connected to an outer rim of the transcranial ultrasound transducer and suspends the antenna within the cavity.

14. The system of claim 13 , further comprising a fluid bath, wherein the fluid bath surrounds the antenna and is positioned within the cavity between the antenna and the inner surface.

15. A system for transcranial magnetic resonance (MR)-guided focused ultrasound, the system comprising:

a transcranial ultrasound transducer configured to apply ultrasound radiation to a head of a patient, the transcranial ultrasound transducer comprising:

a housing defining a cavity that is configured to receive the head of the patient; and

a transducer surface within the housing;

an antenna that is configured to reflect radio frequency (RF) waves; and

a support configured to be connected to the transcranial ultrasound transducer and configured to suspend the antenna within the cavity, wherein:

when the head of the patient is received within the cavity the antenna is between an inner surface of the housing and a top of the head, and

the antenna is passive and does not form an electrical connection.

16. The system of claim 15 , further comprising an MR device configured to image the head while the ultrasound radiation is applied by the transcranial ultrasound transducer to the head.

17. The system of claim 15 , wherein

the housing is concave,

the cavity comprises a bottom opening, and

the antenna is positioned within the cavity between the inner surface and the bottom opening and is configured to reflect RF waves entering the cavity from the bottom opening before the RF waves reach the inner surface.

18. A system for transcranial magnetic resonance (MR)-guided focused ultrasound, the system comprising:

a transcranial ultrasound transducer configured to apply ultrasound radiation to a head of a patient, the transcranial ultrasound transducer comprising:

a housing that is concave, the housing defining a cavity comprising a bottom opening that is configured to receive the head of the patient; and

a transducer surface within the housing;

an antenna that is configured to reflect radio frequency (RF) waves; and

a support configured to be connected to an outer rim of the transcranial ultrasound transducer and configured to suspend the antenna within the cavity, wherein:

when the head of the patient is received within the cavity the antenna is between an inner surface of the housing and a top of the head,

the antenna is passive and does not form an electrical connection, and

the antenna is positioned within the cavity between the inner surface and the bottom opening and is configured to reflect RF waves entering the cavity from the bottom opening before the RF waves reach the inner surface.

19. The system of claim 18 , further comprising a fluid bath, wherein the fluid bath surrounds the antenna and is positioned within the cavity between the antenna and the inner surface.

20. The system of claim 19 , wherein the fluid bath is a water bath.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 22, 2020
From: YAN, XINQIANG; GRISSOM, WILLIAM A.
To: VANDERBILT UNIVERSITY
Reel/Frame 053568/0969 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 10, 2020
From: YAN, XINQIANG; GRISSOM, WILLIAM A.
To: VANDERBILT UNIVERSITY
Reel/Frame 052890/0179 →
Continuity (3)
Provisional Application 62894188 · Aug 30, 2019
Provisional Application 62847748 · May 14, 2019
Related Publication 20200360733A1 · Nov 19, 2020
Cited By (2)
US 12,623,094 US 12,741,161