IP Library › Granted Patent US 11,969,447
Granted Patent B2
US 11,969,447 · App. 17/204,245 · Granted Apr 30, 2024

Use of spray-dried powder derived from lactic acid bacterial strains and herbal extracts for promoting defecation

Inventors: Hsieh-Hsun Ho (Tainan, TW); Ching-Wei Chen (Tainan, TW); Yi-Wei Kuo (Tainan, TW); Yu-Fen Huang (Tainan, TW); Cheng-Chi Lin (Tainan, TW)
Assignee: GLAC BIOTECH CO., LTD.
A61K35/747A23L33/105A23L33/135A61K9/0053A61K35/745A61K36/185A61K36/48A61K36/736A61P1/10A23V2002/00A23V2400/113A23V2400/181A23V2400/515A23V2400/531A61K2035/115
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Quick Facts
Patent No.
US 11,969,447
App. No.
17/204,245
Granted
Apr 30, 2024
Kind
B2
Abstract

A composition for promoting defecation includes a cell culture of at least one lactic acid bacterial strain which is substantially free of cells. The least one lactic acid bacterial strain is selected from the group consisting of Lactobacillus salivarius subsp. salicinius AP-32, Bifidobacterium animalis subsp. lactis CP-9, and Lactobacillus acidophilus TYCA06, which are respectively deposited at the Bioresource Collection and Research Center (BCRC) under accession numbers BCRC 910437, BCRC 910645 and BCRC 910813. Also disclosed is a method for promoting defecation, including administering to a subject in need thereof an effective amount of the composition.

Claims (13)

1. A composition for promoting defecation, comprising:

a spray-dried powder TYCA06 derived from a cell-free culture of Lactobacillus acidophilus TYCA06; and

an herbal extract including a date plum extract, a semen cassiae extract, and a lotus leaf extract,

wherein based on a total weight of said composition, said spray-dried powder of TYCA06 derived from said cell-free culture of Lactobacillus acidophilus TYCA06 is present in an amount ranging from 1 wt % to 10 wt %, said date plum extract is present in an amount ranging from 1 wt % to 20 wt %, said semen cassiae extract is present in an amount ranging from 0.1 wt % to 10 wt %, and said lotus leaf extract is present in an amount ranging from 0.1 wt % to 10 wt %.

2. The composition as claimed in claim 1 , wherein said composition is formulated as a food product.

3. The composition as claimed in claim 1 , wherein said composition is formulated as a pharmaceutical preparation.

4. A method for promoting defecation, comprising administering to a subject in need thereof an effective amount of a composition which includes a spray-dried powder of TYCA06 derived from a cell-free culture of Lactobacillus acidophilus TYCA06, and an herbal extract which includes a date plum extract, a semen cassiae extract, and a lotus leaf extract,

wherein based on a total weight of the composition, the spray-dried powder of TYCA06 derived from the cell-free culture of Lactobacillus acidophilus TYCA06 is present in an amount ranging from 1 wt % to 10 wt %, the date plum extract is present in an amount ranging from 1 wt % to 20 wt %, the semen cassiae extract is present in an amount ranging from 0.1 wt % to 10 wt %, and the lotus leaf extract is present in an amount ranging from 0.1 wt % to 10 wt %.

5. The method as claimed in claim 4 , wherein the composition is formulated as a food product.

6. The method as claimed in claim 4 , wherein the composition is formulated as a pharmaceutical preparation.

7. The method as claimed in claim 4 , wherein the composition is orally administered.

8. The composition as claimed in claim 1 , further comprising a spray-dried powder of AP-32 derived from a cell-free culture of Lactobacillus salivarius subsp. salicinius AP-32.

9. The composition as claimed in claim 1 , further comprising a spray-dried powder of CP-9 derived from a cell-free culture of Bifidobacterium animalis subsp. lactis CP-9.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 24, 2021
From: HO, HSIEH-HSUN; CHEN, CHING-WEI; KUO, YI-WEI; HUANG, YU-FEN; LIN, CHENG-CHI
To: GLAC BIOTECH CO., LTD.
Reel/Frame 056329/0807 →
Priority Claims (1)
TW 109121976 · Jun 30, 2020 · national
Continuity (1)
Related Publication 20210401906A1 · Dec 30, 2021