IP Library Granted Patent US 11,987,647
Granted Patent B2
US 11,987,647 · App. 17/053,684 · Granted May 21, 2024

Cyclic cell-penetrating peptides with one or more hydrophobic residues

Inventor: Dehua Pei (Columbus, OH)
Assignee: Ohio State Innovation Foundation
C07K7/64
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Quick Facts
Patent No.
US 11,987,647
App. No.
17/053,684
Granted
May 21, 2024
Kind
B2
Abstract

Disclosed are cell penetrating peptides and compositions comprising such peptides that can be used to deliver agents to various cell types.

Claims (1)

1. A complex comprising a cargo moiety and a cyclic peptide, wherein at least one atom of the cyclic peptide or at least one lone pair of the cyclic peptide forms a bond to the cargo moiety; wherein the cargo moiety is one or more therapeutic moieties, one or more targeting moieties, or combinations thereof; and the cyclic peptide is selected from CPP 1-2, CPP 1-3, CPP 1-4, CPP 1-10, CPP 1-11, CPP 1-12, CPP 1-13, CPP 1-14, CPP 1-15, CPP 1-16, CPP 1-17, CPP 1-18, CPP 1-19, CPP 1-20, CPP 1-21, CPP 1-22, CPP 1-23, CPP 1-24, and CPP 1-25.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 9, 2023
From: OHIO STATE UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 062320/0709 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 8, 2020
From: PEI, DEHUA
To: OHIO STATE INNOVATION FOUNDATION
Reel/Frame 054358/0243 →
Continuity (2)
Provisional Application 62669146 · May 9, 2018
Related Publication 20210070806A1 · Mar 11, 2021
Cited By (1)
US 12,454,552