Granted Patent
B2
US 11,987,647 · App. 17/053,684 · Granted May 21, 2024
Cyclic cell-penetrating peptides with one or more hydrophobic residues
Assignee:
Ohio State Innovation Foundation
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Abstract
Disclosed are cell penetrating peptides and compositions comprising such peptides that can be used to deliver agents to various cell types.
Claims (1)
1. A complex comprising a cargo moiety and a cyclic peptide, wherein at least one atom of the cyclic peptide or at least one lone pair of the cyclic peptide forms a bond to the cargo moiety; wherein the cargo moiety is one or more therapeutic moieties, one or more targeting moieties, or combinations thereof; and the cyclic peptide is selected from CPP 1-2, CPP 1-3, CPP 1-4, CPP 1-10, CPP 1-11, CPP 1-12, CPP 1-13, CPP 1-14, CPP 1-15, CPP 1-16, CPP 1-17, CPP 1-18, CPP 1-19, CPP 1-20, CPP 1-21, CPP 1-22, CPP 1-23, CPP 1-24, and CPP 1-25.
Assignments (2)
CONFIRMATORY LICENSE
Recorded Jan 9, 2023
From: OHIO STATE UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 062320/0709 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 8, 2020
From: PEI, DEHUA
To: OHIO STATE INNOVATION FOUNDATION
Reel/Frame 054358/0243 →
Continuity (2)
Provisional Application
62669146
· May 9, 2018
Cited By (1)