Physiological feedback systems and methods
The disclosed physiological feedback systems and methods assist with assessing, monitoring and/or treating a patient experiencing a cardiac arrest event. The systems and methods receive multiple inputs and are continuous and/or iterative during a treatment session to provide physiological state trends of the patient. An index of the physiological state of the patient can be derived and confounders, and/or their effects, can be identified, and/or removed, from the index. Additionally, the systems and methods can assist with determining ischemic injury in a patient based on cerebral tissue oxygenation and/or other physiological data.
1. A medical device comprising:
an airway sensor configured to detect a level of carbon dioxide expelled from an airway of an individual;
an oximetry sensor configured to detect a blood oxygenation level of the individual; and
a processor configured to:
determine a threshold based on the level of carbon dioxide expelled from the airway of the individual;
determine that the blood oxygenation level of the individual exceeds the threshold; and
determine that the patient has experienced return of spontaneous circulation (ROSC) based on determining that the blood oxygenation level of the individual exceeds the threshold.
2. The medical device of claim 1 , wherein the oximetry sensor comprises a regional tissue oxygenation (rSO 2 ) sensor.
3. The medical device of claim 1 , further comprising:
a screen configured to visually output an indication of the ROSC; and
a speaker configured to audibly output the indication of the ROSC.
4. A medical device comprising:
a first sensor configured to detect a first physiological parameter indicating a hemodynamic adequacy of an individual, the first physiological parameter being correlated with a confounder;
a second sensor configured to detect a second physiological parameter indicating the hemodynamic adequacy of the individual, the second physiological parameter being non-correlated with the confounder; and
a processor configured to:
determine, based on the first physiological parameter, a threshold;
compare the second physiological parameter to the threshold; and
based on the comparison of the second physiological parameter to the threshold, determine a condition of the individual, wherein the condition comprises a return of spontaneous circulation (ROSC) of the individual, an effectiveness of cardiopulmonary resuscitation (CPR) performed on the individual, or a risk of cardiac re-arrest of the individual.
5. The medical device of claim 4 , wherein the first physiological parameter or the second physiological parameter comprises carbon dioxide expelled from an airway of an individual.
6. The medical device of claim 4 , wherein the first physiological parameter or the second physiological parameter comprises a blood oxygenation level of the individual.
7. The medical device of claim 6 , wherein the first sensor or the second sensor comprises a regional tissue oxygenation (rSO 2 ) sensor configured to detect the blood oxygenation level of the individual.
8. The medical device of claim 4 , wherein the confounder comprises a medication administered to the individual or a treatment administered to the individual.
9. The medical device of claim 4 , further comprising:
a display configured to visually output an indication of the condition.
10. The medical device of claim 4 , further comprising:
a speaker configured to audibly output the indication of the condition.
11. The medical device of claim 4 , further comprising:
a transmitter configured to transmit an indication of the condition of the individual to an external device.
12. A device comprising:
a processor; and
memory storing instructions that, when executed by the processor, cause the processor to perform operations comprising:
determining a threshold based on a first physiological parameter indicative of a hemodynamic adequacy of an individual, the first physiological parameter being correlated with a confounder;
comparing the threshold to a second physiological parameter indicative of the hemodynamic adequacy of the individual, the second physiological parameter being non-correlated with the confounder; and
based on the comparison of the second physiological comparison to the threshold, determine whether the individual is experiencing return of spontaneous circulation (ROSC).
13. The device of claim 12 , further comprising:
a receiver configured to receive data indicative of the first physiological parameter or the second physiological parameter.
14. The device of claim 12 , wherein the first physiological parameter or the second physiological parameter comprises carbon dioxide expelled from an airway of an individual.
15. The device of claim 12 , wherein the first physiological parameter or the second physiological parameter comprises a blood oxygenation level of the individual.
16. The device of claim 12 , wherein the confounder comprises a medication administered to the individual or a treatment administered to the individual.
17. The device of claim 12 , further comprising:
a display configured to visually output an indication of whether the individual is experiencing ROSC; or
a speaker configured to audibly output the indication of the individual is experiencing ROSC.
18. The device of claim 12 , wherein the operations further comprise:
based on the comparison of the second physiological comparison to the threshold, determining an effectiveness of cardiopulmonary resuscitation (CPR) performed on the individual.
19. The device of claim 18 , further comprising:
a transmitter configured to transmit, to an external device, a signal based on whether the individual is experiencing ROSC or the effectiveness of the CPR performed on the individual.
20. The device of claim 19 , wherein the external device comprises a mechanical CPR device.