IP Library › Granted Patent US 12,005,026
Granted Patent B2
US 12,005,026 · App. 17/253,424 · Granted Jun 11, 2024

Infusion bag

Inventors: Torsten Brandenburger (Friedberg, DE); Beatrix Heuel-Hoemmen (Friedberg, DE)
Assignee: Fresenius Kabi Deutschland GmbH
A61J1/10A61J1/1406A61J1/1431A61J1/1481B32B3/08B32B27/08B32B27/302B32B27/32B32B2250/03B32B2250/246B32B2270/00B32B2274/00B32B2307/412B32B2307/51B32B2307/558B32B2307/5825B32B2439/46B32B2439/80
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Quick Facts
Patent No.
US 12,005,026
App. No.
17/253,424
Granted
Jun 11, 2024
Kind
B2
Abstract

The invention relates to a medical package designed as an infusion bag, which medical package is made from multi-layer films that are welded to one another and is filled with a medical liquid for infusion and/or for parenteral nutrition. The invention is described by a medical package designed as an infusion bag, which is made up of a film comprising multiple layers welded to one another and has at least one weld seam, preferably longitudinal and transverse weld seams, and is filled with a medical liquid. The multi-layer film has at least one inner layer of a matrix-phase polymer system, an intermediate layer of a matrix-phase polymer system, and an outer layer of a matrix-phase polymer system. The matrix polymer of the matrix-phase polymer system of the inner layer, the intermediate layer and the outer layer in each case comprises a polypropylene polymer (PP) having defined parts by weight in the individual layers, and the phase polymer of the matrix-phase polymer system of the inner layer, the intermediate layer and the outer layer in each case comprises a styrene-ethylene/butyl-styrene block copolymer (SEBS) having defined parts by weight in the individual layers. The film is characterised in that the styrene-ethylene/butyl-styrene block copolymer (SEBS) of the intermediate layer has a styrene-ethylene/butylene ratio (S/EB M ) and the styrene-ethylene/butylene-styrene block copolymer (SEBS) of the outer layer has a styrene-ethylene/butylene ratio (S/EB A ), in which S/EB A >S/EB M . It has been shown that in this way the mechanical properties of the multi-layer film can be improved, in particular in the event of expansion of the multi-layer film in the region of the weld seams. The improved mechanical properties appear both at room temperature and also at lower temperatures of down to 4° C.

Claims (39)

1. A film comprising:

an inner layer;

an outer layer comprising a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer; and

an intermediate layer disposed between the inner layer and the outer layer, the intermediate layer comprising a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer,

wherein a ratio, by weight, of styrene to ethylene and butylene of the outer layer is between 0.18 and 0.28, and

wherein a ratio, by weight, of styrene to ethylene and butylene of the intermediate layer is between 0.10 and 0.16.

2. The film of claim 1 , wherein the ratio, by weight, of styrene to ethylene and butylene of the outer layer is greater than 1.2 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer.

3. The film of claim 2 , wherein the ratio, by weight, of styrene to ethylene and butylene of the outer layer is greater than 1.5 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer.

4. The film of claim 1 , wherein the polymer of the outer layer is polypropylene, and

wherein the polymer of the intermediate layer is polypropylene.

5. The film of claim 4 , wherein the inner layer comprises a styrene-ethylene/butylene-styrene block copolymer in a matrix of polypropylene.

6. The film of claim 5 , wherein a ratio, by weight, of styrene to ethylene and butylene of the inner layer is greater than the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer.

7. The film of claim 6 , wherein the ratio, by weight, of styrene to ethylene and butylene of the inner layer is greater than 1.2 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer.

8. The film of claim 7 , wherein the ratio, by weight, of styrene to ethylene and butylene of the inner layer is greater than 1.5 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer.

9. The film of claim 5 , wherein a ratio, by weight, of styrene to ethylene and butylene of the inner layer is equal to the ratio, by weight, of styrene to ethylene and butylene of the outer layer.

10. The film of claim 1 , wherein the intermediate layer further comprises a styrene-isoprene-styrene block copolymer in the matrix of the polymer.

11. The film of claim 1 ,

wherein the ratio, by weight, of styrene to ethylene and butylene of the outer layer is between 0.20 and 0.24, and

wherein the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer is between 0.13 and 0.14.

12. The film of claim 1 ,

wherein the inner layer comprises styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer,

wherein a ratio, by weight, of styrene to ethylene and butylene of the inner layer is between 0.18 and 0.28.

13. The film of claim 12 ,

wherein the ratio, by weight, of styrene to ethylene and butylene of the inner layer is between 0.20 and 0.24, and

wherein the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer is between 0.13 and 0.14.

14. A medical package comprising a film, the medical package having at least one seam, and the medical package configured to be filled with a liquid, wherein the film comprises:

an inner layer;

an outer layer comprising a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer; and

an intermediate layer disposed between the inner layer and the outer layer, the intermediate layer comprising a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer,

wherein a ratio, by weight, of styrene to ethylene and butylene of the outer layer is between 0.18 and 0.28, and

wherein a ratio, by weight, of styrene to ethylene and butylene of the intermediate layer is between 0.10 and 0.16.

15. The medical package of claim 14 , wherein the ratio, by weight, of styrene to ethylene and butylene of the outer layer is greater than 1.2 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer.

16. The medical package of claim 14 , wherein the polymer of the outer layer is polypropylene,

wherein the polymer of the matrix of the intermediate layer is polypropylene, and

wherein the inner layer comprises a styrene-ethylene/butylene-styrene block copolymer in a matrix of polypropylene.

17. The medical package of claim 14 , wherein the intermediate layer further comprises a styrene-isoprene-styrene block copolymer in the matrix of the polymer.

18. The medical package of claim 14 ,

wherein the inner layer comprises a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer, and

wherein a ratio, by weight, of styrene to ethylene and butylene of the inner layer is between 0.18 and 0.28.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 12, 2021
From: BRANDENBURGER, TORSTEN; HEUEL-HOEMMEN, BEATRIX
To: FRESENIUS KABI DEUTSCHLAND GMBH
Reel/Frame 054887/0122 →
Priority Claims (1)
EP 18189930 · Aug 21, 2018 · regional
Continuity (1)
Related Publication 20210169739A1 · Jun 10, 2021
Cited By (1)
US 12,390,397