IP Library Granted Patent US 12,013,572
Granted Patent B2
US 12,013,572 · App. 17/708,143 · Granted Jun 18, 2024

Apparatus and methods for high-speed and long depth range imaging using optical coherence tomography

Inventors: Benjamin Vakoc (Arlington, MA); Meena Siddiqui (Boston, MA)
Assignee: The General Hospital Corporation
G02B6/2932A61B5/0066G01B9/02091G01K11/32H01S3/0675H03M1/20A61B5/6826H01S3/06791H01S3/08086H01S3/106H01S3/1062
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,013,572
App. No.
17/708,143
Granted
Jun 18, 2024
Kind
B2
Abstract

Exemplary apparatus can be provided which can include a laser arrangement that is configured to provide a laser radiation, and including an optical cavity. The optical cavity can include a dispersive optical waveguide first arrangement having first and second sides, and which is configured to (i) receive at least one first electro-magnetic radiation at the first side so as to provide at least one second electro-magnetic radiation, and (ii) to receive at least one third electro-magnetic radiation at the second side so as to provide at least one fourth electro-magnetic radiation. The first and second sides are different from one another, and the second and third radiations are related to one another. The optical cavity can also include an active optical modulator second arrangement which can be configured to receive and modulate the fourth radiation so as to provide the first electro-magnetic radiation to the first arrangement. The laser radiation can be associated with at least one of the first, second, third or fourth radiations.

Claims (44)

1. An apparatus for collecting interferometric information, comprising:

an analog to digital converter (ADC) having an input,

the input being configured to receive an interferometric fringe signal from a sample, and

the ADC being configured to digitize the interferometric fringe signal to produce a first digital value having a first number of bits of resolution; and

an averaging engine comprising a storage register configured to store a second digital value having a second number of bits of resolution greater than the first number of bits of resolution,

the averaging engine being configured to:

receive the first digital signal from the ADC, and

calculate a third digital signal having the second number of bits of resolution,

the third digital signal being based on the first digital signal and the second digital signal.

2. The apparatus of claim 1 , wherein the first number of bits of resolution is 8.

3. The apparatus of claim 1 , wherein the second number of bits of resolution is one of 10, 12, 14, or 16.

4. The apparatus of claim 3 , wherein the second number of bits of resolution is 16.

5. The apparatus of claim 1 , wherein the ADC and the averaging engine are implemented on a field programmable gate array.

6. The apparatus of claim 1 , wherein the interferometric fringe signal comprises an A-line generated by an interferometric imaging apparatus,

wherein the apparatus comprises a plurality of averaging engines including the averaging engine, and

wherein the ADC is further configured to:

digitize the interferometric fringe signal to produce a plurality of digital values each having the first number of bits of resolution, and

transmit each of the plurality of digital values to a different one of the plurality of averaging engines.

7. The apparatus of claim 6 , wherein a number of the plurality of digital values generated by the ADC when digitizing the A-line is equal to a number of the plurality of averaging engines.

8. The apparatus of claim 1 , wherein the interferometric fringe signal is based on at least one laser source,

wherein the ADC comprises a clock that is synchronized to an output of the at least one laser source.

9. A method for collecting interferometric information, comprising:

receiving, by an input of an analog to digital converter (ADC), an interferometric fringe signal from a sample;

digitizing, by the ADC, the interferometric fringe signal to produce a first digital value having a first number of bits of resolution;

receiving, by an averaging engine, the first digital signal from the ADC,

storing, by a storage register of the averaging engine, a second digital value having a second number of bits of resolution greater than the first number of bits of resolution; and

calculating, by the averaging engine, a third digital signal having the second number of bits of resolution,

the third digital signal being based on the first digital signal and the second digital signal.

10. The method of claim 9 , wherein digitizing the interferometric fringe signal to produce a first digital value having a first number of bits of resolution further comprises:

digitizing the interferometric fringe signal to produce a first digital value having a 8 bits of resolution.

11. The method of claim 9 , wherein storing a second digital value having a second number of bits of resolution further comprises:

storing a second digital value having one of 10, 12, 14, or 16 bits of resolution.

12. The method of claim 11 , wherein storing a second digital value having a second number of bits of resolution further comprises:

storing a second digital value having 16 bits of resolution.

13. The method of claim 9 , wherein the ADC and the averaging engine are implemented on a field programmable gate array.

14. The method of claim 9 , wherein the interferometric fringe signal comprises an A-line generated by an interferometric imaging apparatus,

wherein the apparatus comprises a plurality of averaging engines including the averaging engine, and

wherein the method further comprises:

digitizing, by the ADC, the interferometric fringe signal to produce a plurality of digital values each having the first number of bits of resolution, and

transmitting, by the ADC, each of the plurality of digital values to a different one of the plurality of averaging engines.

15. The method of claim 14 , wherein a number of the plurality of digital values generated by the ADC when digitizing the A-line is equal to a number of the plurality of averaging engines.

16. The method of claim 9 , wherein the interferometric fringe signal is based on at least one laser source, and

wherein the method further comprises:

synchronizing a clock of the ADC to an output of the at least one laser source.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2022
From: VAKOC, BENJAMIN; SIDDIQUI, MEENA
To: GENERAL HOSPITAL CORPORATION, THE
Reel/Frame 059439/0044 →
Continuity (5)
Continuation 17106690 · Nov 30, 2020
Continuation 16077294
Provisional Application 62310365 · Mar 18, 2016
Provisional Application 62294822 · Feb 12, 2016
Related Publication 20220221267A1 · Jul 14, 2022