Surgical tool
Presented herein are dual-function surgical tools for insertion of implantable stimulating assemblies, such as intra-cochlear stimulating assemblies. In addition to facilitating intra-operative positioning of a stimulating assembly within a recipient (e.g., operating to guide the stimulating assembly of an implantable medical device into position), the surgical tool also includes a plurality of electrodes configured to apply an electroporation electrical field to a recipient's nerve cells to enable introduction of treatment substance into the nerve cells.
1. A surgical tool comprising:
a sheath configured to be inserted into a body chamber within the body of a recipient to guide a stimulating assembly of an implantable medical device into position within the body chamber,
wherein the sheath comprises a plurality of electrodes.
2. The surgical tool of claim 1 , wherein the sheath forms a tube through which the stimulating assembly is advanced.
3. The surgical tool of claim 1 , wherein the sheath comprises a thin-film circuit, and wherein the plurality of electrodes are formed on an outer surface of the thin-film circuit.
4. The surgical tool of claim 1 , wherein the surgical tool has a proximal portion attached to the sheath that facilitates manipulation of the surgical tool during surgery.
5. The surgical tool of claim 1 , wherein the body chamber comprises a cochlea of the recipient, and wherein the sheath is configured for insertion through a round window of the cochlea.
6. The surgical tool of claim 1 , wherein the plurality of electrodes are formed into two or more functional groups of electrodes.
7. The surgical tool of claim 6 , wherein the two or more functional groups of electrodes include a distal group of electrodes comprising electrodes located relatively closer to a distal end of the sheath, and a proximal group of electrodes comprising electrodes located relatively closer to a proximal end of the sheath.
8. The surgical tool of claim 1 , wherein the surgical tool has at least one electrical connector configured to electrically connect the electrodes to a current source.
9. The surgical tool of claim 8 , wherein the at least one electrical connector is configured to electrically connect the surgical tool to an external current source.
10. The surgical tool of claim 1 , wherein the plurality of electrodes are electrically isolated from the implantable medical device.
11. The surgical tool of claim 1 , wherein the surgical tool includes a substance delivery mechanism configured to deliver a treatment substance into the body chamber.
12. The surgical tool of claim 11 , wherein the substance delivery mechanism comprises a substance delivery lumen configured to deliver the treatment substance into the body chamber.
13. The surgical tool of claim 12 , wherein the substance delivery lumen is a collapsible lumen that is located inside the sheath.
14. An insertion tool for a stimulating assembly, comprising:
an insertion guide member configured to receive the stimulating assembly therein, wherein a distal portion of the insertion guide member is configured to be positioned within a body chamber of a recipient; and
one or more electrodes disposed on the distal portion of the insertion guide member, wherein the one or more electrodes are configured to apply an electrical field to the recipient.
15. The insertion tool of claim 14 , further comprising:
a least one electrical connector configured to electrically connect the one or more electrodes to a current source; and
one or more leads extending from the one or more electrodes to the at least one electrical connector.
16. The insertion tool of claim 14 , wherein the one or more electrodes comprise a plurality of electrodes formed into two or more functional groups of electrodes.
17. The insertion tool of claim 16 , wherein the two or more functional groups of electrodes include a distal group of electrodes comprising electrodes located relatively closer to a distal end of the insertion guide member, and a proximal group of electrodes comprising electrodes located relatively closer to a proximal end of the insertion guide member.
18. The insertion tool of claim 14 , wherein an outer surface of the insertion guide member comprises a thin-film circuit, and wherein the one or more electrodes are formed as part of the thin-film circuit.
19. The insertion tool of claim 14 , further comprising:
a substance delivery mechanism configured to deliver a treatment substance into the body chamber.
20. The insertion tool of claim 19 , wherein the substance delivery mechanism is a collapsible lumen that is located inside the insertion guide member.
21. The insertion tool of claim 19 , wherein the treatment substance is at least one biological agent selected from the group including: Deoxyribonucleic acid (DNA), Ribonucleic acid (RNA) molecules, brain-derived neurotrophic factors, peptides, RNAi and viral vectors.
22. The insertion tool of claim 14 , wherein the insertion guide member forms a tube through which the stimulating assembly is advanced.
23. The insertion tool of claim 22 , wherein the insertion guide member includes a longitudinal seam that is configured to splay open as a force is applied to an interior surface of the insertion guide member via advancement of the stimulating assembly.
24. The insertion tool of claim 23 , wherein the treatment substance is at least one biological agent selected from the group including: Deoxyribonucleic acid (DNA), Ribonucleic acid (RNA) molecules, brain-derived neurotrophic factors, peptides, RNAi and viral vectors.