Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia
There is herein provided a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein the ring containing Q 1 to Q 5 , and the groups R 1 , R 2 and R 3 , have meanings as provided in the description.
1. A method of treating hyperglycaemia comprising administering to a patient in need thereof a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt thereof, wherein the compound is of the following formula:
2. A method of treating a disorder selected from type 2 diabetes, Rabson-Mendenhall syndrome, Donohue's syndrome, Type A syndrome of insulin resistance, Type B syndrome of insulin resistance, HAIR-AN syndrome, pseudoacromegaly, and lipodystrophy comprising administering to a patient in need thereof a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt thereof, wherein the compound is of the following formula:
3. The method of claim 2 , wherein the disorder is type 2 diabetes.
4. The method of claim 2 , wherein the disorder is Rabson-Mendenhall syndrome.
5. The method of claim 2 , wherein the disorder is Donohue's syndrome.
6. The method of claim 2 , wherein the disorder is Type A syndrome of insulin resistance.
7. The method of claim 2 , wherein the disorder is Type B syndrome of insulin resistance.
8. The method of claim 2 , wherein the disorder is pseudoacromegaly.
9. The method of claim 2 , wherein the disorder is HAIR-AN syndrome.
10. The method of claim 2 , wherein the disorder is lipodystrophy.